Tramadol and Sabril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tramadol (tramadol hydrochloride) and Sabril (vigabatrin). Common drug interactions include atrial fibrillation among females and bradypnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Tramadol and Sabril. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Tramadol?

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 235,798 Tramadol users. Check the latest studies of Tramadol.

What is Sabril?

Sabril has active ingredients of vigabatrin. eHealthMe is studying from 12,445 Sabril users. Check the latest studies of Sabril.

On Jul, 29, 2026

12 people who take Tramadol and Sabril together, and have interactions are studied.

What are the common drug interactions of Tramadol and Sabril, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bladder cancer
Cardiac disorder
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colon cancer
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Depression
Diarrhoea

male:

Bradypnoea (an abnormally slow respiratory rate)
Coma (state of unconsciousness lasting more than six hours)
Eye swelling
Feeding disorder (when children refuse to eat certain food groups)
Lip swelling
Sinusitis (inflammation of sinus)
Stomatitis (inflammation of mucous membrane of mouth)
Swelling face

What are the common drug interactions of Tramadol and Sabril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bladder cancer
Cardiac disorder
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colon cancer
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Diarrhoea
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Drug withdrawal convulsions

50-59:

Eye swelling
Feeding disorder (when children refuse to eat certain food groups)
Lip swelling
Sinusitis (inflammation of sinus)
Stomatitis (inflammation of mucous membrane of mouth)
Swelling face

60+:

n/a

What are the existing conditions these people have? *

Partial Seizures (seizures which affect only a part of the brain at onset): 7 people, 58.33%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 16.67%
Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 1 person, 8.33%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 8.33%
Angiomyolipoma (most common benign tumour of the kidney): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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