Tramadol and Tambocor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tramadol (tramadol hydrochloride) and Tambocor (flecainide acetate). Common drug interactions include lumbar vertebral fracture among females and impaired healing among males.

The phase IV clinical study analyzes what interactions people have when they take Tramadol and Tambocor. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Tramadol?

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 235,800 Tramadol users. Check the latest studies of Tramadol.

What is Tambocor?

Tambocor has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,621 Tambocor users. Check the latest studies of Tambocor.

On Aug, 04, 2026

17 people who take Tramadol and Tambocor together, and have interactions are studied.

Tramadol and Tambocor drug interactions.

What are the common drug interactions of Tramadol and Tambocor, by gender? *:

female:

Lumbar vertebral fracture
Myalgia (muscle pain)
Rebound effect (take-back effect)
Spinal fracture (fracture in one of vertebrae)
Thoracic vertebral fracture
Abdominal discomfort
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Arthralgia (joint pain)
Asthenia (weakness)

male:

Impaired healing
Myopathy (a muscular disease in which the muscle fibres do not function)
Acne (skin problems that cause pimples)
Dyspnoea (difficult or laboured respiration)
Pulmonary embolism (blockage of the main artery of the lung)
Swelling
Urinary retention (the inability to completely or partially empty the bladder)

What are the common drug interactions of Tramadol and Tambocor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Pathological fracture (broken bone caused by disease)
Lumbar vertebral fracture
Rebound effect (take-back effect)
Spinal fracture (fracture in one of vertebrae)
Thoracic vertebral fracture

60+:

Impaired healing
Myopathy (a muscular disease in which the muscle fibres do not function)
Arthralgia (joint pain)
Asthenia (weakness)
Blood pressure increased
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Chills (felling of cold)
Diarrhoea
Drug hypersensitivity
Dry mouth

What are the existing conditions these people have? *

Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 4 people, 23.53%
Osteoporosis (bones weak and more likely to break): 4 people, 23.53%
Depression: 4 people, 23.53%
Extrasystoles: 4 people, 23.53%
Skin Ulcer: 2 people, 11.76%
Nausea And Vomiting: 2 people, 11.76%
Nausea (feeling of having an urge to vomit): 2 people, 11.76%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 11.76%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 11.76%
Migraine (headache): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Tramadol and Tambocor?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously