Trandolapril and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trandolapril (trandolapril) and Colace (docusate ). Common drug interactions include pulmonary embolism among females and abscess oral among males.

The phase IV clinical study analyzes what interactions people have when they take Trandolapril and Colace. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Trandolapril?

Trandolapril has active ingredients of trandolapril. It is often used in high blood pressure. eHealthMe is studying from 2,682 Trandolapril users. Check the latest studies of Trandolapril.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.



On Jul, 12, 2026

26 people who take Trandolapril and Colace together, and have interactions are studied.

Trandolapril and Colace drug interactions.

What are the common drug interactions of Trandolapril and Colace, by gender? *:

female:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Thrombotic stroke (stroke due to clot formation)
  3. Transverse sinus thrombosis (a blood clot in transverse sinus)
  4. Dyspnoea (difficult or laboured respiration)
  5. Abdominal distension
  6. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  7. Candidiasis (candidiasis or thrush is a fungal infection)
  8. Chest pain
  9. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  10. Decreased appetite

male:

  1. Abscess oral (abscess in the mouth)
  2. Alanine aminotransferase increased
  3. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  4. Gingival bleeding (bleeding gums)
  5. Gingival oedema (swelling of gums)
  6. Gynaecomastia (enlargement of the gland tissue of the male breast)
  7. Haematemesis (vomiting of blood)
  8. Induration (thickening of tissue)
  9. Infection
  10. Irritable bowel syndrome

What are the common drug interactions of Trandolapril and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Asthenia (weakness)
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Emotional distress
  6. General physical health deterioration (weak health status)
  7. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  8. Injury
  9. Pain
  10. Pulmonary embolism (blockage of the main artery of the lung)

40-49:

  1. Aspartate aminotransferase increased
  2. Bone disorder
  3. Cellulitis (infection under the skin)
  4. Clavicle fracture
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Erythema (redness of the skin)
  7. Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)
  8. Face oedema (swelling of face)
  9. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  10. Gingival bleeding (bleeding gums)

50-59:

  1. Cardiac arrest
  2. Fluid retention (an abnormal accumulation of fluid in the blood)
  3. Oedema peripheral (superficial swelling)
  4. Renal impairment (severely reduced kidney function)

60+:

  1. Asthenia (weakness)
  2. Dyspnoea (difficult or laboured respiration)
  3. Candidiasis (candidiasis or thrush is a fungal infection)
  4. Decreased appetite
  5. Dehydration (dryness resulting from the removal of water)
  6. Electrolyte imbalance
  7. Failure to thrive (inadequate weight gain and physical growth in children)
  8. Pneumonia
  9. Urinary tract infection
  10. Vomiting

What are the existing conditions these people have? *

  1. Pain: 6 people, 23.08%
  2. Multiple Myeloma (cancer of the plasma cells): 6 people, 23.08%
  3. Immunodeficiency Common Variable: 4 people, 15.38%
  4. Nausea (feeling of having an urge to vomit): 4 people, 15.38%
  5. Stress And Anxiety: 3 people, 11.54%
  6. Asthma: 3 people, 11.54%
  7. Headache (pain in head): 3 people, 11.54%
  8. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 11.54%
  9. Premenstrual Syndrome: 3 people, 11.54%
  10. Acne (skin problems that cause pimples): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

Do you take Trandolapril and Colace?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Trandolapril and Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trandolapril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trandolapril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colace and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on trandolapril and docusate (the active ingredients of Trandolapril and Colace, respectively), and Trandolapril and Colace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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