Trandolapril and Dyazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trandolapril (trandolapril) and Dyazide (hydrochlorothiazide; triamterene). Common drug interactions include hyperreflexia among females and skin infection among males.

The phase IV clinical study analyzes what interactions people have when they take Trandolapril and Dyazide. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Trandolapril?

Trandolapril has active ingredients of trandolapril. It is often used in high blood pressure. eHealthMe is studying from 2,682 Trandolapril users. Check the latest studies of Trandolapril.

What is Dyazide?

Dyazide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 11,506 Dyazide users. Check the latest studies of Dyazide.



On Jul, 17, 2026

11 people who take Trandolapril and Dyazide together, and have interactions are studied.

Trandolapril and Dyazide drug interactions.

What are the common drug interactions of Trandolapril and Dyazide, by gender? *:

female:

  1. Hyperreflexia (overactive or over responsive reflexes)
  2. Hypersensitivity
  3. Hyperthyroidism (over activity of the thyroid gland)
  4. Hyporeflexia (a condition of below normal or absent reflexes)
  5. Hypotonia (low muscle tone)
  6. Lacunar infarction (a type of stroke)
  7. Localised infection (infection at the single location)
  8. Muscle atrophy (a decrease in the mass of the muscle)
  9. Nausea (feeling of having an urge to vomit)
  10. Nervousness

male:

  1. Skin infection
  2. Cellulitis (infection under the skin)

What are the common drug interactions of Trandolapril and Dyazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Skin infection
  2. Cellulitis (infection under the skin)
  3. Anaemia (lack of blood)
  4. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  5. Psoriasis (immune-mediated disease that affects the skin)

60+:

  1. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  2. Asthenia (weakness)
  3. Hypokalaemia (low potassium)
  4. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  5. Hypoxia (low oxygen in tissues)
  6. Nausea (feeling of having an urge to vomit)
  7. Nephrogenic anaemia (anaemia due to kidney disease)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Renal failure (kidney dysfunction)
  10. Renal tubular necrosis (death of kidney tubules)

What are the existing conditions these people have? *

  1. Hyperglycemia (high blood sugar): 4 people, 36.36%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 27.27%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 18.18%
  4. Pain: 2 people, 18.18%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 18.18%
  6. Cellulitis (infection under the skin): 2 people, 18.18%
  7. Stress And Anxiety: 1 person, 9.09%
  8. Psoriasis (immune-mediated disease that affects the skin): 1 person, 9.09%
  9. Multiple Myeloma (cancer of the plasma cells): 1 person, 9.09%
  10. Insomnia (sleeplessness): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Trandolapril and Dyazide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Trandolapril and Dyazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trandolapril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dyazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trandolapril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dyazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on trandolapril and hydrochlorothiazide; triamterene (the active ingredients of Trandolapril and Dyazide, respectively), and Trandolapril and Dyazide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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