Tranexamic acid and Adrenalin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranexamic acid (tranexamic acid) and Adrenalin (epinephrine). Common drug interactions include hyperaesthesia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Tranexamic acid and Adrenalin. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,687 Tranexamic acid users. Check the latest studies of Tranexamic acid.

What is Adrenalin?

Adrenalin has active ingredients of epinephrine. eHealthMe is studying from 853 Adrenalin users. Check the latest studies of Adrenalin.



On Jul, 07, 2026

33 people who take Tranexamic acid and Adrenalin together, and have interactions are studied.

Tranexamic acid and Adrenalin drug interactions.

What are the common drug interactions of Tranexamic Acid and Adrenalin, by gender? *:

female:

  1. Hyperaesthesia
  2. Abdominal distension
  3. Anaemia (lack of blood)
  4. Cardiac arrest
  5. Coagulopathy (blood's ability to clot is impaired)
  6. Dysphonia (speech disorder attributable to a disorder of phonation)
  7. Hepatic failure (liver failure)
  8. Acidosis (build-up of carbon dioxide in the blood)
  9. Acute respiratory failure
  10. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)

male:

  1. Pneumonia
  2. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  3. Asthenia (weakness)
  4. Burkholderia test positive
  5. Dizziness
  6. Blood creatine increased
  7. Cardiac arrest
  8. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  9. Dehydration (dryness resulting from the removal of water)
  10. Pulmonary oedema (fluid accumulation in the lungs)

What are the common drug interactions of Tranexamic Acid and Adrenalin, by age (0-1 to 60+)? *:

0-1:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Blood creatine phosphokinase increased
  4. Blood urea increased
  5. Procalcitonin increased
  6. Pyrexia (fever)
  7. Renal impairment (severely reduced kidney function)

2-9:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Blood creatine increased
  4. Blood creatine phosphokinase increased
  5. Blood urea increased
  6. Procalcitonin increased
  7. Pyrexia (fever)
  8. Renal impairment (severely reduced kidney function)

10-19:

n/a

20-29:

n/a

30-39:

  1. Diarrhoea
  2. Hepatitis (inflammation of the liver)
  3. Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney)
  4. Hypotension (abnormally low blood pressure)
  5. Hypoxia (low oxygen in tissues)
  6. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  7. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  8. Renal failure (kidney dysfunction)
  9. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

40-49:

n/a

50-59:

n/a

60+:

  1. Hyperaesthesia
  2. Cardiac arrest
  3. Cardiogenic shock (inadequate circulation of blood)
  4. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  5. Haematemesis (vomiting of blood)
  6. Haemorrhage (bleeding)
  7. Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
  8. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  9. Ventricular fibrillation (abnormally irregular heart rhythm)
  10. Pneumonia

What are the existing conditions these people have? *

  1. Sedation: 20 people, 60.61%
  2. Local Anaesthesia: 13 people, 39.39%
  3. Pain: 13 people, 39.39%
  4. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 24.24%
  5. Anaesthesia: 6 people, 18.18%
  6. High Blood Pressure: 5 people, 15.15%
  7. Anaemia (lack of blood): 3 people, 9.09%
  8. Haemorrhage (bleeding): 3 people, 9.09%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 9.09%
  10. Hepatotoxicity (chemical-driven liver damage): 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tranexamic acid and Adrenalin:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tranexamic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adrenalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tranexamic acid and drugs from A to Z:

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Browse all interactions between Adrenalin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tranexamic acid and epinephrine (the active ingredients of Tranexamic acid and Adrenalin, respectively), and Tranexamic acid and Adrenalin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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