Tranexamic acid and Bactrim ds drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranexamic acid (tranexamic acid) and Bactrim ds (sulfamethoxazole; trimethoprim). Common drug interactions include platelet count decreased among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Tranexamic acid and Bactrim ds. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,687 Tranexamic acid users. Check the latest studies of Tranexamic acid.

What is Bactrim ds?

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

12 people who take Tranexamic acid and Bactrim ds together, and have interactions are studied.

Tranexamic acid and Bactrim ds drug interactions.

What are the common drug interactions of Tranexamic Acid and Bactrim Ds, by gender? *:

female:

Platelet count decreased
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)
Splenomegaly (enlargement of spleen)
Surgery
Sepsis (a severe blood infection that can lead to organ failure and death)

male:

Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Dyspnoea (difficult or laboured respiration)
Enterococcal infection
Myalgia (muscle pain)
Neuralgia (pain in one or more nerves)
Pyrexia (fever)
Sinus congestion (blockage of sinus)
Vomiting

What are the common drug interactions of Tranexamic Acid and Bactrim Ds, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Sepsis (a severe blood infection that can lead to organ failure and death)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

40-49:

n/a

50-59:

Gout (uric acid crystals building up in the body)

60+:

Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Dyspnoea (difficult or laboured respiration)
Enterococcal infection
Myalgia (muscle pain)
Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)
Pyrexia (fever)
Sinus congestion (blockage of sinus)
Vomiting

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 25.00%
Thrombocytopenia (decrease of platelets in blood): 2 people, 16.67%
Hepatic Steatosis (fatty liver disease): 2 people, 16.67%
Blood Magnesium Decreased: 2 people, 16.67%
Constipation: 2 people, 16.67%
Depression: 2 people, 16.67%
Escherichia Bacteraemia (presence of bacteria escherichia coli in the blood): 2 people, 16.67%
Fever: 2 people, 16.67%
Pain: 2 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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