Tranexamic acid and Colchicine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranexamic acid (tranexamic acid) and Colchicine (colchicine). Common drug interactions include schnitzler's syndrome among females and septic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Tranexamic acid and Colchicine. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,687 Tranexamic acid users. Check the latest studies of Tranexamic acid.

What is Colchicine?

Colchicine has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 21,826 Colchicine users. Check the latest studies of Colchicine.



On Jul, 07, 2026

43 people who take Tranexamic acid and Colchicine together, and have interactions are studied.

Tranexamic acid and Colchicine drug interactions.

What are the common drug interactions of Tranexamic Acid and Colchicine, by gender? *:

female:

  1. Schnitzler's syndrome (a rare disease characterized by chronic hives (urticaria) and periodic fever, bone pain and joint pain)
  2. Swelling
  3. Swollen tongue (swelling of tongue)
  4. Syncope (loss of consciousness with an inability to maintain postural tone)
  5. Upper limb fracture
  6. Urinary retention (the inability to completely or partially empty the bladder)
  7. Weight decreased
  8. Weight increased
  9. Joint dislocation (a joint position is changed from normal position)
  10. Breast cancer

male:

  1. Septic shock (shock due to blood infection)
  2. Haematuria (presence of blood in urine)
  3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  4. Colitis (inflammation of colon)
  5. Depressed level of consciousness
  6. Gangrene (body tissue dies)
  7. Insomnia (sleeplessness)
  8. Limb injury
  9. Pneumonia
  10. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the common drug interactions of Tranexamic Acid and Colchicine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Weight increased
  2. Anosmia (partial or complete loss of the sense of smell)
  3. Arthralgia (joint pain)
  4. Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Cough
  7. Decreased appetite
  8. Fall
  9. Headache (pain in head)
  10. Malaise (a feeling of general discomfort or uneasiness)

10-19:

  1. Gastroenteritis (inflammation of stomach and intestine)

20-29:

n/a

30-39:

  1. Drug ineffective
  2. Angioedema (rapid swelling of the dermis)
  3. Discomfort
  4. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  5. Swelling
  6. Swollen tongue (swelling of tongue)

40-49:

  1. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  2. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  3. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

50-59:

  1. Septic shock (shock due to blood infection)
  2. Delirium (wild excitement)
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Haemoglobin decreased
  5. Hypotension (abnormally low blood pressure)
  6. Infection
  7. Sinus bradycardia (an unusually slow heartbeat due to heart disease)
  8. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)

60+:

  1. Haematuria (presence of blood in urine)
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Depressed level of consciousness
  4. Gangrene (body tissue dies)
  5. Insomnia (sleeplessness)
  6. Limb injury
  7. Pneumonia
  8. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  9. Pulmonary tuberculosis (lungs tuberculosis)
  10. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the existing conditions these people have? *

  1. High Blood Pressure: 12 people, 27.91%
  2. Constipation: 11 people, 25.58%
  3. Cough: 9 people, 20.93%
  4. Coughing Up Blood: 9 people, 20.93%
  5. Back Pain: 8 people, 18.60%
  6. Nausea (feeling of having an urge to vomit): 7 people, 16.28%
  7. Hepatic Steatosis (fatty liver disease): 6 people, 13.95%
  8. Hyperglycemia (high blood sugar): 6 people, 13.95%
  9. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 6 people, 13.95%
  10. Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 6 people, 13.95%

* Approximation only. Some reports may have incomplete information.

Do you take Tranexamic acid and Colchicine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tranexamic acid and Colchicine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tranexamic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Colchicine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tranexamic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colchicine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tranexamic acid and colchicine (the active ingredients of Tranexamic acid and Colchicine, respectively), and Tranexamic acid and Colchicine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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