Tranexamic acid and Depakene drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranexamic acid (tranexamic acid) and Depakene (valproic acid). Common drug interactions include headache among females and pneumonia aspiration among males.

The phase IV clinical study analyzes what interactions people have when they take Tranexamic acid and Depakene. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,687 Tranexamic acid users. Check the latest studies of Tranexamic acid.

What is Depakene?

Depakene has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 14,776 Depakene users. Check the latest studies of Depakene.

On Jul, 11, 2026

15 people who take Tranexamic acid and Depakene together, and have interactions are studied.

Tranexamic acid and Depakene drug interactions.

What are the common drug interactions of Tranexamic Acid and Depakene, by gender? *:

female:

Headache (pain in head)
Pyrexia (fever)
Rash
Decreased appetite
Depression
Drug level decreased
General physical health deterioration (weak health status)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Haemorrhage (bleeding)
Hypokalaemia (low potassium)

male:

Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Anaemia (lack of blood)
Chest pain
Depressed level of consciousness
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Dyspnoea (difficult or laboured respiration)
Electrolyte imbalance
Erythema multiforme (a type of hypersensitivity reaction)
Erythropenia (a deficiency in the number of red blood cells)

What are the common drug interactions of Tranexamic Acid and Depakene, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac failure
Cardiogenic shock (inadequate circulation of blood)
Clonic convulsion (long lasting seizure)
Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Gastrointestinal hypomotility (less activity of the intestinal tract)
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Phlebitis infective (inflammation of the walls of a vein-infective)
Platelet count decreased
Pneumonia
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

30-39:

Headache (pain in head)
Pyrexia (fever)
Rash
Decreased appetite

40-49:

Hyperlipidaemia (presence of excess lipids in the blood)
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Nasopharyngitis (inflammation of the nasopharynx)
Neck pain
Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

50-59:

n/a

60+:

Anaemia (lack of blood)
Brain contusion (a form of traumatic brain injury)
Depressed level of consciousness
Depression
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Dyspnoea (difficult or laboured respiration)
Electrolyte imbalance
Erythema multiforme (a type of hypersensitivity reaction)
Erythropenia (a deficiency in the number of red blood cells)

What are the existing conditions these people have? *

Insomnia (sleeplessness): 4 people, 26.67%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 3 people, 20.00%
Nasopharyngitis (inflammation of the nasopharynx): 3 people, 20.00%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 20.00%
Constipation: 3 people, 20.00%
Headache (pain in head): 2 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 13.33%
Depression: 2 people, 13.33%
High Blood Pressure: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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