Tranexamic acid and Hydroxyurea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranexamic acid (tranexamic acid) and Hydroxyurea (hydroxyurea). Common drug interactions include febrile neutropenia among females and supraventricular extrasystoles among males.

The phase IV clinical study analyzes what interactions people have when they take Tranexamic acid and Hydroxyurea. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,687 Tranexamic acid users. Check the latest studies of Tranexamic acid.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

On Jul, 15, 2026

48 people who take Tranexamic acid and Hydroxyurea together, and have interactions are studied.

Tranexamic acid and Hydroxyurea drug interactions.

What are the common drug interactions of Tranexamic Acid and Hydroxyurea, by gender? *:

female:

Febrile neutropenia (fever with reduced white blood cells)
Colitis (inflammation of colon)
Death
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Haemoglobin decreased
Mucosal inflammation (infection of mucous membrane)
Platelet count decreased
Subdural haemorrhage (bleeding between the skull and the surface of the brain)
Hydronephrosis (water inside the kidney)

male:

Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Sinusitis fungal (fungal infection of sinus)
Cerebral haemorrhage (bleeding within the brain)
Pneumonia fungal
Renal impairment (severely reduced kidney function)
Arrhythmia (irregular heartbeat)
Blood potassium decreased
Capillary leak syndrome (capillary leaks plasma)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)

What are the common drug interactions of Tranexamic Acid and Hydroxyurea, by age (0-1 to 60+)? *:

0-1:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Premature baby

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Mucosal inflammation (infection of mucous membrane)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Death
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)

40-49:

Diarrhoea
Hydronephrosis (water inside the kidney)
Nephrolithiasis (calculi in the kidneys)
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Acute respiratory distress syndrome
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood potassium decreased
Drug toxicity

50-59:

Cerebral haemorrhage (bleeding within the brain)
Arrhythmia (irregular heartbeat)
Febrile neutropenia (fever with reduced white blood cells)

60+:

Febrile neutropenia (fever with reduced white blood cells)
Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
Colitis (inflammation of colon)
Pneumonia fungal
Subdural haemorrhage (bleeding between the skull and the surface of the brain)
Acute circulatory failure (shock)
Blood creatinine increased
Blood potassium decreased
Capillary leak syndrome (capillary leaks plasma)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 23 people, 47.92%
Nausea (feeling of having an urge to vomit): 16 people, 33.33%
Constipation: 15 people, 31.25%
High Blood Pressure: 12 people, 25.00%
Pain: 12 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 22.92%
Hypokalemia (low potassium): 10 people, 20.83%
Asthma: 9 people, 18.75%
Haemorrhage (bleeding): 8 people, 16.67%
Insomnia (sleeplessness): 7 people, 14.58%

* Approximation only. Some reports may have incomplete information.

Do you take Tranexamic acid and Hydroxyurea?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously