Tranexamic acid and Isosorbide mononitrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranexamic acid (tranexamic acid) and Isosorbide mononitrate (isosorbide mononitrate). Common drug interactions include chronic kidney disease among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Tranexamic acid and Isosorbide mononitrate. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,687 Tranexamic acid users. Check the latest studies of Tranexamic acid.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

On Jul, 27, 2026

18 people who take Tranexamic acid and Isosorbide mononitrate together, and have interactions are studied.

Tranexamic acid and Isosorbide mononitrate drug interactions.

What are the common drug interactions of Tranexamic Acid and Isosorbide Mononitrate, by gender? *:

female:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Renal failure (kidney dysfunction)
Arthralgia (joint pain)
Haemoglobin decreased
Oropharyngeal blistering (blister of oropharynx)
Purpura (purplish discoloration of the skin)
Rash erythematous (redness of the skin)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Rectal haemorrhage (bleeding from anus)

male:

Pneumonia
Blood creatinine increased
Blood potassium increased
Blood pressure decreased
Chronic kidney disease
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Heart rate increased
Hepatocellular damage (liver damage)
Nephrogenic anaemia (anaemia due to kidney disease)
Pyrexia (fever)

What are the common drug interactions of Tranexamic Acid and Isosorbide Mononitrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Haemoglobin decreased
Oropharyngeal blistering (blister of oropharynx)
Purpura (purplish discoloration of the skin)
Rash erythematous (redness of the skin)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Rectal haemorrhage (bleeding from anus)
Renal failure acute (rapid kidney dysfunction)
Vaginal haemorrhage (vaginal bleeding)

40-49:

n/a

50-59:

n/a

60+:

Pneumonia
Blood creatinine increased
Pyrexia (fever)
Death
Febrile neutropenia (fever with reduced white blood cells)
Lung infection
Blood chloride decreased
Blood potassium increased
Blood pressure decreased
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 38.89%
High Blood Pressure: 4 people, 22.22%
High Blood Cholesterol: 3 people, 16.67%
Dyspnea (difficult or laboured breathing): 3 people, 16.67%
Gout (uric acid crystals building up in the body): 3 people, 16.67%
Depression: 3 people, 16.67%
Pain: 3 people, 16.67%
Constipation: 3 people, 16.67%
Insomnia (sleeplessness): 3 people, 16.67%
Itching: 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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