Tranexamic acid and Locoid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranexamic acid (tranexamic acid) and Locoid (hydrocortisone butyrate). Common drug interactions include febrile neutropenia among females and neuropathy peripheral among males.

The phase IV clinical study analyzes what interactions people have when they take Tranexamic acid and Locoid. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,687 Tranexamic acid users. Check the latest studies of Tranexamic acid.

What is Locoid?

Locoid has active ingredients of hydrocortisone butyrate. eHealthMe is studying from 1,996 Locoid users. Check the latest studies of Locoid.



On Jul, 04, 2026

21 people who take Tranexamic acid and Locoid together, and have interactions are studied.

Tranexamic acid and Locoid drug interactions.

What are the common drug interactions of Tranexamic Acid and Locoid, by gender? *:

female:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Ascites (accumulation of fluid in the abdominal cavity)
  3. Pyrexia (fever)
  4. Alopecia areata (patchy baldness that typically begins with rapid hair loss)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Gastroenteritis (inflammation of stomach and intestine)
  8. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  9. Systemic lupus erythematosus rash (an autoimmune disease, which means the body's immune system mistakenly attacks healthy tissue and causes the rashes)
  10. Tinea cruris (an infection of the groin caused by a fungus)

male:

  1. Neuropathy peripheral (surface nerve damage)
  2. Anaemia (lack of blood)
  3. Hyperkeratosis (thickening of the outer layer of the skin)
  4. Ingrowing nail
  5. Alanine aminotransferase increased
  6. Aspartate aminotransferase increased
  7. Blood creatine phosphokinase increased
  8. Haemoglobin decreased
  9. Haemorrhage (bleeding)
  10. Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the common drug interactions of Tranexamic Acid and Locoid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Pyrexia (fever)
  2. Malaise (a feeling of general discomfort or uneasiness)

30-39:

  1. Alopecia areata (patchy baldness that typically begins with rapid hair loss)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Gastroenteritis (inflammation of stomach and intestine)
  5. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  6. Systemic lupus erythematosus rash (an autoimmune disease, which means the body's immune system mistakenly attacks healthy tissue and causes the rashes)
  7. Tinea cruris (an infection of the groin caused by a fungus)

40-49:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Ascites (accumulation of fluid in the abdominal cavity)
  3. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  4. Pyrexia (fever)

50-59:

  1. Spinal compression fracture (fracture due to spinal compression on bone)
  2. Conjunctivitis (pink eye)
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  5. Hyperkeratosis (thickening of the outer layer of the skin)
  6. Ingrowing nail
  7. Blood creatine phosphokinase increased
  8. Haemoglobin decreased
  9. Haemorrhage (bleeding)
  10. Hypoglycaemia (deficiency of glucose in the bloodstream)

60+:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Pyrexia (fever)
  4. Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

  1. Constipation: 11 people, 52.38%
  2. Abdominal Pain: 6 people, 28.57%
  3. Stomatitis (inflammation of mucous membrane of mouth): 6 people, 28.57%
  4. Ascites (accumulation of fluid in the abdominal cavity): 6 people, 28.57%
  5. Cheilitis (infection of lips): 6 people, 28.57%
  6. Pharyngitis (inflammation of the pharynx, causing a sore throat): 6 people, 28.57%
  7. Ovarian Cancer (cancer of ovary): 6 people, 28.57%
  8. Oropharyngeal Pain: 6 people, 28.57%
  9. Erythema Multiforme (a type of hypersensitivity reaction): 6 people, 28.57%
  10. Insomnia (sleeplessness): 5 people, 23.81%

* Approximation only. Some reports may have incomplete information.

Do you take Tranexamic acid and Locoid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tranexamic acid and Locoid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tranexamic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Locoid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tranexamic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Locoid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tranexamic acid and hydrocortisone butyrate (the active ingredients of Tranexamic acid and Locoid, respectively), and Tranexamic acid and Locoid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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