Tranexamic acid and Valproic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranexamic acid (tranexamic acid) and Valproic acid (valproic acid). Common drug interactions include confusional state among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Tranexamic acid and Valproic acid. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,687 Tranexamic acid users. Check the latest studies of Tranexamic acid.

What is Valproic acid?

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.

On Aug, 09, 2026

14 people who take Tranexamic acid and Valproic acid together, and have interactions are studied.

Tranexamic acid and Valproic acid drug interactions.

What are the common drug interactions of Tranexamic Acid and Valproic Acid, by gender? *:

female:

Confusional state
Hypokinesia (decreased bodily movement)
Quadriparesis (muscle weakness affecting all four limbs)
Hypoaesthesia (reduced sense of touch or sensation)
Somnolence (a state of near-sleep, a strong desire for sleep)
Speech disorder

male:

Pyrexia (fever)
Application site burn
Epistaxis (bleed from the nose)
Granuloma skin (a small area of inflammation on skin due to tissue injury)
Vomiting
Breath sounds
Chills (felling of cold)
Crepitations (noises are produced by the rubbing of parts one against the other)
Drug ineffective
Dyskinesia (abnormality or impairment of voluntary movement)

What are the common drug interactions of Tranexamic Acid and Valproic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blood sodium decreased
Death
Epistaxis (bleed from the nose)
Granuloma skin (a small area of inflammation on skin due to tissue injury)
Pyrexia (fever)
Vomiting
Chills (felling of cold)
Drug ineffective
Dyskinesia (abnormality or impairment of voluntary movement)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)

20-29:

Breath sounds
Crepitations (noises are produced by the rubbing of parts one against the other)
Dyspnoea (difficult or laboured respiration)
Interstitial lung disease
Pyrexia (fever)

30-39:

Confusional state
Hypoaesthesia (reduced sense of touch or sensation)
Somnolence (a state of near-sleep, a strong desire for sleep)
Speech disorder

40-49:

n/a

50-59:

Pancreatitis (inflammation of pancreas)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Aggression
Hospitalisation
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Neutropenia (an abnormally low number of neutrophils)
White blood cell count decreased
Haemolytic anaemia (anaemia due to haemolysis)

60+:

Confusional state
Hypokinesia (decreased bodily movement)
Quadriparesis (muscle weakness affecting all four limbs)
Application site burn
Application site erythema (redness of the skin at application site)
Application site pruritus (application site severe itching of the skin)
Application site rash
Rash erythematous (redness of the skin)
Rash pruritic (redness with itching)

What are the existing conditions these people have? *

Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 5 people, 35.71%
General Anaesthesia: 4 people, 28.57%
High Blood Pressure: 3 people, 21.43%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 7.14%
Sedation: 1 person, 7.14%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 7.14%
Proctalgia (pain in the rectum): 1 person, 7.14%
Paranasal Sinus Discomfort: 1 person, 7.14%
Haemorrhage (bleeding): 1 person, 7.14%
Dyskinesia (abnormality or impairment of voluntary movement): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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