Tranxene and Chantix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranxene (clorazepate dipotassium) and Chantix (varenicline tartrate). Common drug interactions include tachycardia among females and abnormal dreams among males.

The phase IV clinical study analyzes what interactions people have when they take Tranxene and Chantix. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Tranxene?

Tranxene has active ingredients of clorazepate dipotassium. It is often used in stress and anxiety. eHealthMe is studying from 6,550 Tranxene users. Check the latest studies of Tranxene.

What is Chantix?

Chantix has active ingredients of varenicline tartrate. It is often used in quit smoking. eHealthMe is studying from 89,889 Chantix users. Check the latest studies of Chantix.

On Jul, 11, 2026

35 people who take Tranxene and Chantix together, and have interactions are studied.

What are the common drug interactions of Tranxene and Chantix, by gender? *:

female:

Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Therapeutic response decreased (less preventive response)
Urinary retention (the inability to completely or partially empty the bladder)
Nausea (feeling of having an urge to vomit)
Irritability
Abnormal dreams
Dizziness
Weight decreased
Nervousness
Weight increased

male:

Abnormal dreams
Blood pressure increased
Nausea (feeling of having an urge to vomit)
Nervousness
Nightmare (unpleasant dream)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Screaming (a long loud piercing cry)
Cataract (clouding of the lens inside the eye)
Constipation

What are the common drug interactions of Tranxene and Chantix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Therapeutic response decreased (less preventive response)

40-49:

Oropharyngeal blistering (blister of oropharynx)
Abnormal behaviour
Completed suicide (act of taking one's own life)
Depression
Headache (pain in head)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Nightmare (unpleasant dream)

50-59:

Irritability
Weight decreased
Anger
Ankle fracture
Depression
Dizziness
Fear
Hypoaesthesia (reduced sense of touch or sensation)
Influenza
Nausea (feeling of having an urge to vomit)

60+:

Nausea (feeling of having an urge to vomit)
Nervousness
Skin exfoliation (removal of the oldest dead skin cells)
Weight increased
Activities of daily living impaired
Arthralgia (joint pain)
Blood glucose decreased
Chest discomfort
Confusional state
Drug ineffective

What are the existing conditions these people have? *

Depression: 8 people, 22.86%
High Blood Pressure: 4 people, 11.43%
Nervousness: 3 people, 8.57%
Cough: 3 people, 8.57%
Asthma: 3 people, 8.57%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 5.71%
Panic Disorder: 2 people, 5.71%
Pain: 2 people, 5.71%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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