Tranxene and Gentamicin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranxene (clorazepate dipotassium) and Gentamicin (gentamicin sulfate). Common drug interactions include skin erosion among females and chills among males.

The phase IV clinical study analyzes what interactions people have when they take Tranxene and Gentamicin. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Tranxene?

Tranxene has active ingredients of clorazepate dipotassium. It is often used in stress and anxiety. eHealthMe is studying from 6,550 Tranxene users. Check the latest studies of Tranxene.

What is Gentamicin?

Gentamicin has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 21,654 Gentamicin users. Check the latest studies of Gentamicin.



On Jul, 08, 2026

86 people who take Tranxene and Gentamicin together, and have interactions are studied.

Tranxene and Gentamicin drug interactions.

What are the common drug interactions of Tranxene and Gentamicin, by gender? *:

female:

  1. Skin erosion (a discontinuity of the skin)
  2. Asterixis (flapping tremor, or liver flap)
  3. Bladder disorder
  4. Catheter site infection (infection at the site of insertion)
  5. Chest pain
  6. Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins)
  7. Coma (state of unconsciousness lasting more than six hours)
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Gastric ulcer (stomach ulcer)
  10. Hepatitis acute

male:

  1. Chills (felling of cold)
  2. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Cytotoxic oedema (swelling from being toxic to cells matrials)
  5. Dysarthria (speech disorder)
  6. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  7. Headache (pain in head)
  8. Hemiplegia (paralysis of one side of the body)
  9. Onycholysis (detachment of the nail from the nail bed)
  10. Pruritus (severe itching of the skin)

What are the common drug interactions of Tranxene and Gentamicin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Muscular weakness (muscle weakness)
  2. Pneumonia
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Death

10-19:

  1. Chills (felling of cold)
  2. Clumsiness (a lack of coordination or elegance)
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Cytotoxic oedema (swelling from being toxic to cells matrials)
  5. Dysarthria (speech disorder)
  6. Headache (pain in head)
  7. Hemiplegia (paralysis of one side of the body)
  8. Viith nerve paralysis
  9. Facial palsy (paralysis of face nerve)

20-29:

n/a

30-39:

  1. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  2. Inflammation
  3. Prothrombin time shortened
  4. Scar
  5. Sense of oppression (sense of heavy burden)
  6. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  7. Toxic skin eruption (skin breakdown due to toxic substance)
  8. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  9. Pyrexia (fever)
  10. Anaemia (lack of blood)

40-49:

  1. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
  4. Multi-organ failure (multisystem organ failure)
  5. Graft versus host disease in intestine (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body and damages intestinal mucosal membrane)
  6. Haematuria (presence of blood in urine)
  7. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  8. Oedema (fluid collection in tissue)
  9. Skin lesion
  10. Eschar (dead tissue that falls off (sheds) from healthy skin)

50-59:

  1. Hypertriglyceridaemia (excess of triglycerides in the blood)
  2. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  3. Enterococcal infection
  4. Lung disorder (lung disease)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Pneumomediastinum (air is present in the mediastinum)
  7. Catheter related infection
  8. Catheter site infection (infection at the site of insertion)
  9. Chest pain
  10. Dysphagia (a condition in which swallowing is difficult or painful)

60+:

  1. Aplasia (defective development or congenital absence of an organ or tissue)
  2. Chills (felling of cold)
  3. Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
  4. Asterixis (flapping tremor, or liver flap)
  5. Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins)
  6. Coma (state of unconsciousness lasting more than six hours)
  7. Depressed level of consciousness
  8. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  9. Gastric ulcer (stomach ulcer)
  10. General physical health deterioration (weak health status)

What are the existing conditions these people have? *

  1. Cerebral Palsy: 45 people, 52.33%
  2. Pain: 6 people, 6.98%

* Approximation only. Some reports may have incomplete information.

Do you take Tranxene and Gentamicin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tranxene and Gentamicin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tranxene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gentamicin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tranxene and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gentamicin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on clorazepate dipotassium and gentamicin sulfate (the active ingredients of Tranxene and Gentamicin, respectively), and Tranxene and Gentamicin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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