Travatan and Actonel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Travatan (travoprost) and Actonel (risedronate sodium). Common drug interactions include atrial fibrillation among females and gynaecomastia among males.

The phase IV clinical study analyzes what interactions people have when they take Travatan and Actonel. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Travatan?

Travatan has active ingredients of travoprost. It is often used in glaucoma. eHealthMe is studying from 13,103 Travatan users. Check the latest studies of Travatan.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.



On Jul, 26, 2026

85 people who take Travatan and Actonel together, and have interactions are studied.

Travatan and Actonel drug interactions.

What are the common drug interactions of Travatan and Actonel, by gender? *:

female:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  3. Syncope (loss of consciousness with an inability to maintain postural tone)
  4. Femur fracture
  5. Bone disorder
  6. Dizziness
  7. Nausea (feeling of having an urge to vomit)
  8. Gait disturbance
  9. Leukaemia (blood or bone marrow cancer)
  10. Muscular weakness (muscle weakness)

male:

  1. Gynaecomastia (enlargement of the gland tissue of the male breast)
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Ataxia (loss of full control of bodily movements)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
  6. Blood bicarbonate increased
  7. Blood chloride decreased
  8. Blood creatine phosphokinase increased
  9. Blood glucose increased
  10. Blood urea increased

What are the common drug interactions of Travatan and Actonel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Gynaecomastia (enlargement of the gland tissue of the male breast)

40-49:

n/a

50-59:

  1. Staphylococcal infection (an infection with staphylococcus bacteria)
  2. Abdominal pain
  3. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  4. Pain in extremity
  5. Chest discomfort
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Cough
  8. Dehydration (dryness resulting from the removal of water)
  9. Dyspepsia (indigestion)
  10. Ear infection

60+:

  1. Fall
  2. Bone disorder
  3. Nausea (feeling of having an urge to vomit)
  4. Nervousness
  5. Abasia (inability to walk)
  6. Arthralgia (joint pain)
  7. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  8. Dyspnoea (difficult or laboured respiration)
  9. Endometrial cancer
  10. Exostosis (formation of new bone on the surface of a bone)

What are the existing conditions these people have? *

  1. High Blood Pressure: 13 people, 15.29%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 14.12%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 12 people, 14.12%
  4. Depression: 8 people, 9.41%
  5. Joint Pain: 7 people, 8.24%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 8.24%
  7. Spondyloarthropathy (any joint disease of the vertebral column): 5 people, 5.88%
  8. Sleep Disorder: 5 people, 5.88%
  9. Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 5.88%
  10. Asthma: 5 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Travatan and Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Travatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Travatan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Actonel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on travoprost and risedronate sodium (the active ingredients of Travatan and Actonel, respectively), and Travatan and Actonel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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