Trazodone hydrochloride and Fluoride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trazodone hydrochloride (trazodone hydrochloride) and Fluoride (fluoride). Common drug interactions include abdominal distension among females and eye inflammation among males.

The phase IV clinical study analyzes what interactions people have when they take Trazodone hydrochloride and Fluoride. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Trazodone hydrochloride?

Trazodone hydrochloride has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 23,018 Trazodone hydrochloride users. Check the latest studies of Trazodone hydrochloride.

What is Fluoride?

Fluoride has active ingredients of fluoride. eHealthMe is studying from 2,301 Fluoride users. Check the latest studies of Fluoride.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

11 people who take Trazodone hydrochloride and Fluoride together, and have interactions are studied.

Trazodone hydrochloride and Fluoride drug interactions.

What are the common drug interactions of Trazodone Hydrochloride and Fluoride, by gender? *:

female:

Abdominal distension
Abdominal pain
Aphasia (damage to the parts of the brain that control language)
Constipation
Decreased appetite
Diarrhoea
Drug ineffective
Optic neuritis (optic nerve inflammation)
Oral mucosal erythema (redness of the mucous membrane of mouth)
Oral pain

male:

Eye inflammation
Visual acuity reduced (reduced clearness of vision)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Compulsive shopping
Cough
Dental caries
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Disability
Ejection fraction decreased (systolic heart failure)
Fatigue (feeling of tiredness)

What are the common drug interactions of Trazodone Hydrochloride and Fluoride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Sinusitis (inflammation of sinus)

30-39:

n/a

40-49:

n/a

50-59:

Anaemia (lack of blood)
Anxiety
Blunted affect (lack of emotional reactivity)
Compulsive shopping
Cough
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Disability
Folliculitis (infection of hair root)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

60+:

Eye inflammation
Visual acuity reduced (reduced clearness of vision)
Ejection fraction decreased (systolic heart failure)
Hypotension (abnormally low blood pressure)
Intermittent claudication
Periodontal disease (disease that attacks the gum and bone and around the teeth)
Poor quality sleep
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Thrombosis (formation of a blood clot inside a blood vessel)
Endophthalmitis (inflammation of the internal coats of the eye)

What are the existing conditions these people have? *

Hepatocellular Carcinoma (liver cancer): 2 people, 18.18%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 9.09%
Inflammation: 1 person, 9.09%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 9.09%
Blood Pressure Abnormal: 1 person, 9.09%
Cardiac Disorder: 1 person, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 9.09%
Depression: 1 person, 9.09%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 9.09%
Erection Problems: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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