Trazodone hydrochloride and Kadcyla drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trazodone hydrochloride (trazodone hydrochloride) and Kadcyla (ado-trastuzumab emtansine). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Trazodone hydrochloride and Kadcyla. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Trazodone hydrochloride?

Trazodone hydrochloride has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 23,016 Trazodone hydrochloride users. Check the latest studies of Trazodone hydrochloride.

What is Kadcyla?

Kadcyla has active ingredients of ado-trastuzumab emtansine. eHealthMe is studying from 5,813 Kadcyla users. Check the latest studies of Kadcyla.



On Aug, 11, 2026

44 people who take Trazodone hydrochloride and Kadcyla together, and have interactions are studied.

Trazodone hydrochloride and Kadcyla drug interactions.

What are the common drug interactions of Trazodone Hydrochloride and Kadcyla, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Headache (pain in head)
  3. Asthenia (weakness)
  4. General physical health deterioration (weak health status)
  5. Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
  6. Iron deficiency anaemia
  7. Neutropenia (an abnormally low number of neutrophils)
  8. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  9. Hypertension (high blood pressure)
  10. Infection

male:

n/a

What are the common drug interactions of Trazodone Hydrochloride and Kadcyla, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. White blood cell count decreased
  2. Hemianopia (blindness or reduction in vision in one half of the visual field due to damage of the optic pathways in the brain)
  3. Nausea (feeling of having an urge to vomit)
  4. Skin fissures (a crack in the skin)
  5. Thrombocytopenia (decrease of platelets in blood)

40-49:

  1. Blood bilirubin increased
  2. Gamma-glutamyltransferase increased
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Aphthous ulcer (mouth ulcer)
  5. Asthenia (weakness)
  6. Diarrhoea
  7. General physical health deterioration (weak health status)
  8. Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
  9. Iron deficiency anaemia
  10. Neutropenia (an abnormally low number of neutrophils)

50-59:

n/a

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Headache (pain in head)
  3. White blood cell count decreased
  4. Cough
  5. Fatigue (feeling of tiredness)
  6. C-reactive protein increased
  7. Overdose
  8. Restlessness (not able to rest)
  9. Angina pectoris (chest pain due to ischemia of the heart muscle)
  10. Blindness

What are the existing conditions these people have? *

  1. Diarrhea: 31 people, 70.45%
  2. Nausea (feeling of having an urge to vomit): 15 people, 34.09%
  3. Breast Cancer Metastatic: 14 people, 31.82%
  4. Dyspnea (difficult or laboured breathing): 12 people, 27.27%
  5. Abdominal Pain Upper: 10 people, 22.73%
  6. Gastroenteritis Radiation (radiation induced inflammation of stomach and intestine): 10 people, 22.73%
  7. Osteonecrosis Of Jaw (death of bone of jaw): 10 people, 22.73%
  8. Oedema Peripheral (superficial swelling): 10 people, 22.73%
  9. Mucosal Inflammation (infection of mucous membrane): 10 people, 22.73%
  10. Joint Pain: 10 people, 22.73%

* Approximation only. Some reports may have incomplete information.

Do you take Trazodone hydrochloride and Kadcyla?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Trazodone hydrochloride and Kadcyla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trazodone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Kadcyla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trazodone hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kadcyla and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on trazodone hydrochloride and ado-trastuzumab emtansine (the active ingredients of Trazodone hydrochloride and Kadcyla, respectively), and Trazodone hydrochloride and Kadcyla (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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