Tremfya and Enstilar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tremfya (guselkumab) and Enstilar (betamethasone dipropionate; calcipotriene). Common drug interactions include myocardial infarction among females and anal cancer among males.

The phase IV clinical study analyzes what interactions people have when they take Tremfya and Enstilar. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Tremfya?

Tremfya has active ingredients of guselkumab. eHealthMe is studying from 22,557 Tremfya users. Check the latest studies of Tremfya.

What is Enstilar?

Enstilar has active ingredients of betamethasone dipropionate; calcipotriene. eHealthMe is studying from 1,673 Enstilar users. Check the latest studies of Enstilar.



On Aug, 03, 2026

37 people who take Tremfya and Enstilar together, and have interactions are studied.

Tremfya and Enstilar drug interactions.

What are the common drug interactions of Tremfya and Enstilar, by gender? *:

female:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Urinary tract disorder
  3. Breast cancer
  4. Pyrexia (fever)
  5. Drug ineffective
  6. Chest pain
  7. Diarrhoea
  8. Vomiting
  9. Abdominal discomfort
  10. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

male:

  1. Anal cancer
  2. Prostate cancer
  3. Flatulence (flatus expelled through the anus)
  4. Fungal infection
  5. Pleural infection (infection of membrane of lungs)
  6. Psoriasis (immune-mediated disease that affects the skin)
  7. Toothache (tooth pain)
  8. Urinary tract infection
  9. Epstein-barr virus infection
  10. B-cell lymphoma (blood cancer affecting b cells)

What are the common drug interactions of Tremfya and Enstilar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Diarrhoea

30-39:

  1. Epstein-barr virus infection
  2. Uterine polyp (a mass in the inner lining of the uterus)
  3. Diarrhoea
  4. Flatulence (flatus expelled through the anus)
  5. Fungal infection
  6. Toothache (tooth pain)

40-49:

  1. B-cell lymphoma (blood cancer affecting b cells)
  2. Menstruation irregular
  3. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)

50-59:

  1. Drug ineffective
  2. Abdominal discomfort
  3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  4. Diarrhoea
  5. Psoriasis (immune-mediated disease that affects the skin)
  6. Shoulder operation

60+:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Urinary tract disorder
  3. Pneumonia
  4. Pericardial effusion (fluid around the heart)
  5. Rash
  6. Urticaria (rash of round, red welts on the skin that itch intensely)
  7. Cellulitis (infection under the skin)
  8. Inflammation
  9. Urinary tract infection
  10. Breast cancer

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 34 people, 91.89%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 8.11%
  3. Hidradenitis (chronic disease of a type of sweat gland): 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

Do you take Tremfya and Enstilar?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tremfya and Enstilar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tremfya:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Enstilar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tremfya and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Enstilar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on guselkumab and betamethasone dipropionate; calcipotriene (the active ingredients of Tremfya and Enstilar, respectively), and Tremfya and Enstilar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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