Treprostinil and Exidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Treprostinil (treprostinil) and Exidine (chlorhexidine gluconate). Common drug interactions include nausea among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Treprostinil and Exidine. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Treprostinil?

Treprostinil has active ingredients of treprostinil. eHealthMe is studying from 7,695 Treprostinil users. Check the latest studies of Treprostinil.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.



On Jul, 14, 2026

19 people who take Treprostinil and Exidine together, and have interactions are studied.

Treprostinil and Exidine drug interactions.

What are the common drug interactions of Treprostinil and Exidine, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Vomiting
  3. Diarrhoea
  4. Dizziness
  5. Headache (pain in head)
  6. Presyncope
  7. Seasonal allergy (allergic condition due to certain season)
  8. Infusion site rash
  9. Ligament sprain (ligament stretched)
  10. Rash

male:

  1. Arthralgia (joint pain)
  2. Cardiac failure congestive
  3. Spinal fusion surgery
  4. Wound dehiscence (a surgical incision reopens either internally or externally)
  5. Fluid overload (too much fluid in the blood)
  6. Pulmonary hypertension (increase in blood pressure in the lung artery)
  7. Fall
  8. Aortic valve stenosis (narrowing of the aortic valve)
  9. Failure to thrive (inadequate weight gain and physical growth in children)
  10. Hypotension (abnormally low blood pressure)

What are the common drug interactions of Treprostinil and Exidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abscess neck (neck abscesses)
  2. Application site irritation
  3. Cardiac failure
  4. Catheter site rash
  5. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  6. Device related infection
  7. Dyspnoea (difficult or laboured respiration)
  8. Headache (pain in head)
  9. Pulmonary hypertension (increase in blood pressure in the lung artery)

40-49:

  1. Abdominal pain
  2. Alanine aminotransferase increased
  3. Arthralgia (joint pain)
  4. Aspartate aminotransferase increased
  5. Back pain
  6. Blood bilirubin increased
  7. Cardiac arrest
  8. Disease progression
  9. Dyspnoea exertional (breathlessness or shortness of breath)
  10. Electrolyte imbalance

50-59:

  1. Anaemia (lack of blood)
  2. Anxiety
  3. Asthenia (weakness)
  4. Blood potassium decreased
  5. Chest discomfort
  6. Chest pain
  7. Depression
  8. Diarrhoea
  9. Dizziness
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Catheter site pain
  2. Diarrhoea
  3. Gastric haemorrhage (bleeding stomach)
  4. Haemoglobin decreased
  5. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  6. Haemorrhage (bleeding)
  7. Headache (pain in head)
  8. Infusion site pruritus (severe itching at infusion site)
  9. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  10. Pain in jaw

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 18 people, 94.74%
  2. Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 5.26%
  3. Fainting (loss of consciousness and postural tone): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Treprostinil and Exidine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Treprostinil and Exidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Treprostinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Exidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Treprostinil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on treprostinil and chlorhexidine gluconate (the active ingredients of Treprostinil and Exidine, respectively), and Treprostinil and Exidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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