Treprostinil and Loraz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Treprostinil (treprostinil) and Loraz (lorazepam). Common drug interactions include pneumonia among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Treprostinil and Loraz. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Treprostinil?

Treprostinil has active ingredients of treprostinil. eHealthMe is studying from 7,695 Treprostinil users. Check the latest studies of Treprostinil.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.



On Jul, 15, 2026

29 people who take Treprostinil and Loraz together, and have interactions are studied.

Treprostinil and Loraz drug interactions.

What are the common drug interactions of Treprostinil and Loraz, by gender? *:

female:

  1. Pneumonia
  2. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  3. Regurgitation (expulsion of material)
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  7. Tachypnoea (a condition of rapid breathing over 20 per minute)
  8. Thrombocytosis
  9. Wheezing (a high-pitched whistling sound made while you breath)
  10. White blood cell count increased

male:

  1. Abdominal discomfort
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Heart rate increased
  4. Mood altered (changes in mood)
  5. Nausea (feeling of having an urge to vomit)
  6. Palpitations (feelings or sensations that your heart is pounding or racing)
  7. Psychomotor hyperactivity (feelings of extreme restlessness)
  8. Urticaria (rash of round, red welts on the skin that itch intensely)
  9. Vomiting
  10. Abdominal pain

What are the common drug interactions of Treprostinil and Loraz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal discomfort
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Abdominal pain upper
  4. Acne (skin problems that cause pimples)
  5. Chest pain
  6. Diarrhoea
  7. Dizziness
  8. Dyspnoea exertional (breathlessness or shortness of breath)
  9. Flushing (the warm, red condition of human skin)
  10. Headache (pain in head)

20-29:

n/a

30-39:

  1. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  2. Overdose
  3. Drug ineffective
  4. Oedema peripheral (superficial swelling)
  5. Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
  6. Pulmonary hypertension (increase in blood pressure in the lung artery)
  7. Unresponsive to stimuli

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Cardiac failure acute
  4. Pain of skin
  5. Rash papular (redness with papule)
  6. Right ventricular failure (right half of the heart fails to work)
  7. Skin burning sensation
  8. Syncope (loss of consciousness with an inability to maintain postural tone)
  9. Upper respiratory tract infection
  10. Viral infection

50-59:

  1. Hypervolaemia (abnormally increased volume of blood)
  2. Hypotension (abnormally low blood pressure)
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  4. Increased appetite
  5. Infusion site pain
  6. Joint stiffness
  7. Lung disorder (lung disease)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Multi-organ failure (multisystem organ failure)
  10. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

60+:

  1. Blood pressure increased
  2. Diarrhoea
  3. Rash
  4. Sinusitis (inflammation of sinus)
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Dyspnoea (difficult or laboured respiration)
  7. Asthenia (weakness)
  8. Death
  9. Haematemesis (vomiting of blood)
  10. Drug hypersensitivity

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 21 people, 72.41%
  2. Pulmonary Hypertension (increase in blood pressure in the lung artery): 7 people, 24.14%
  3. Insomnia (sleeplessness): 4 people, 13.79%
  4. Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 6.90%
  5. Depression: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Treprostinil and Loraz?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Treprostinil and Loraz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Treprostinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Loraz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Treprostinil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Loraz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on treprostinil and lorazepam (the active ingredients of Treprostinil and Loraz, respectively), and Treprostinil and Loraz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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