Tresiba and Lanoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tresiba (insulin degludec) and Lanoxin (digoxin). Common drug interactions include hypoglycaemic coma among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Tresiba and Lanoxin. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Tresiba?

Tresiba has active ingredients of insulin degludec. It is often used in type 1 diabetes. eHealthMe is studying from 20,677 Tresiba users. Check the latest studies of Tresiba.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.



On Jul, 16, 2026

22 people who take Tresiba and Lanoxin together, and have interactions are studied.

Tresiba and Lanoxin drug interactions.

What are the common drug interactions of Tresiba and Lanoxin, by gender? *:

female:

  1. Hypoglycaemic coma (coma due to deficiency of glucose in the bloodstream)
  2. Arthralgia (joint pain)
  3. Cardiac failure congestive
  4. Chills (felling of cold)
  5. Chronic kidney disease
  6. Cough
  7. Decreased appetite
  8. Dry mouth
  9. Fatigue (feeling of tiredness)
  10. Flushing (the warm, red condition of human skin)

male:

  1. Back pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Dysphemia (stammering or stuttering)
  4. Gravitational oedema (abnormally large fluid volume in the circulatory system makes obese)
  5. Headache (pain in head)
  6. Lung infection
  7. Oxygen saturation decreased
  8. Pain in jaw
  9. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  10. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the common drug interactions of Tresiba and Lanoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Cardiac failure congestive
  2. Chronic kidney disease
  3. Renal failure (kidney dysfunction)

50-59:

  1. Abscess limb (limb infection)
  2. Anal abscess
  3. Cellulitis (infection under the skin)
  4. Genital abscess (build up of pus in genital)
  5. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  6. Panic attack
  7. Perirectal abscess
  8. Subcutaneous abscess

60+:

  1. Hypoglycaemic coma (coma due to deficiency of glucose in the bloodstream)
  2. Back pain
  3. Diabetic foot
  4. Diarrhoea
  5. Dysphemia (stammering or stuttering)
  6. Gravitational oedema (abnormally large fluid volume in the circulatory system makes obese)
  7. Headache (pain in head)
  8. Lung infection
  9. Oxygen saturation decreased
  10. Pain in jaw

What are the existing conditions these people have? *

  1. Diabetes: 10 people, 45.45%
  2. High Blood Pressure: 7 people, 31.82%
  3. Pain: 4 people, 18.18%
  4. Type 2 Diabetes: 3 people, 13.64%
  5. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 13.64%
  6. Cardiac Disorder: 3 people, 13.64%
  7. Prostate Cancer: 2 people, 9.09%
  8. High Blood Cholesterol: 2 people, 9.09%
  9. Heart Disease: 2 people, 9.09%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Tresiba and Lanoxin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tresiba and Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tresiba:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tresiba and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lanoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on insulin degludec and digoxin (the active ingredients of Tresiba and Lanoxin, respectively), and Tresiba and Lanoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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