Treximet and Miralax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Treximet (naproxen sodium; sumatriptan succinate) and Miralax (polyethylene glycol 3350). Common drug interactions include impaired gastric emptying among females and atrioventricular block among males.

The phase IV clinical study analyzes what interactions people have when they take Treximet and Miralax. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Treximet?

Treximet has active ingredients of naproxen sodium; sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 1,904 Treximet users. Check the latest studies of Treximet.

What is Miralax?

Miralax has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 81,754 Miralax users. Check the latest studies of Miralax.

On Jul, 16, 2026

35 people who take Treximet and Miralax together, and have interactions are studied.

What are the common drug interactions of Treximet and Miralax, by gender? *:

female:

Impaired gastric emptying
Initial insomnia (feeling of inadequate or poor-quality sleep)
Tendon rupture (tear of tendon)
Therapeutic response unexpected
Vomiting
Contusion (a type of hematoma of tissue in which capillaries)
Fall
Headache (pain in head)
Joint injury
Joint swelling

male:

Atrioventricular block (heart block)
Angina pectoris (chest pain due to ischemia of the heart muscle)

What are the common drug interactions of Treximet and Miralax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Atrioventricular block (heart block)

40-49:

Atrioventricular block (heart block)

50-59:

Contusion (a type of hematoma of tissue in which capillaries)
Fall
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Joint injury
Joint swelling
Post procedural infection
Tendon rupture (tear of tendon)
Surgery
Cholecystitis (infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

60+:

Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Depression
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dry mouth
Faecal incontinence (a lack of control over passing stool)
Flatulence (flatus expelled through the anus)
Headache (pain in head)
Myalgia (muscle pain)
Nuchal rigidity (a resistance to flexion of the neck)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 27 people, 77.14%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 31.43%
Pain: 5 people, 14.29%
Depression: 5 people, 14.29%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 11.43%
Headache (pain in head): 3 people, 8.57%
Sleep Apnea Syndrome: 2 people, 5.71%
Blood Glucose Increased: 2 people, 5.71%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 5.71%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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