Trichlormethiazide and Repaglinide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trichlormethiazide (trichlormethiazide) and Repaglinide (repaglinide). Common drug interactions include arthralgia among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Trichlormethiazide and Repaglinide. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Trichlormethiazide?

Trichlormethiazide has active ingredients of trichlormethiazide. eHealthMe is studying from 2,613 Trichlormethiazide users. Check the latest studies of Trichlormethiazide.

What is Repaglinide?

Repaglinide has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 8,226 Repaglinide users. Check the latest studies of Repaglinide.



On Jul, 21, 2026

20 people who take Trichlormethiazide and Repaglinide together, and have interactions are studied.

Trichlormethiazide and Repaglinide drug interactions.

What are the common drug interactions of Trichlormethiazide and Repaglinide, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Pneumonia
  3. Abnormal faeces (abnormal stool)
  4. Acute respiratory failure
  5. Aortic arteriosclerosis (hardening of the aortic arteries)
  6. Aortic disorder
  7. Basophil count increased
  8. Blood glucose increased
  9. Blood magnesium increased
  10. Blood potassium increased

male:

  1. Abdominal distension
  2. Constipation
  3. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
  4. Cardiac failure congestive
  5. Cardiomegaly (increased size of heart than normal)
  6. Cataract (clouding of the lens inside the eye)
  7. Cholangitis acute (rapid infection of bile duct)
  8. Diabetic retinopathy (damage to the retina caused by complications of diabetes)
  9. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  10. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)

What are the common drug interactions of Trichlormethiazide and Repaglinide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Alanine aminotransferase increased
  2. Aortic valve incompetence
  3. Aspartate aminotransferase increased
  4. Blood glucose increased
  5. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
  6. Cardiac failure congestive
  7. Cardiomegaly (increased size of heart than normal)
  8. Cataract (clouding of the lens inside the eye)
  9. Diabetic retinopathy (damage to the retina caused by complications of diabetes)
  10. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)

60+:

  1. Arthralgia (joint pain)
  2. Pneumonia
  3. Blood urea increased
  4. Bone callus excessive (excessive bony deposit formed between and around the broken ends of bone fractures)
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Femur fracture
  7. Flatulence (flatus expelled through the anus)
  8. Haemoglobin decreased
  9. Injury
  10. Joint range of motion decreased (disease of joint movement)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 15 people, 75.00%
  2. High Blood Pressure: 12 people, 60.00%
  3. Productive Cough: 11 people, 55.00%
  4. Arrhythmias (irregular heartbeat): 11 people, 55.00%
  5. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 11 people, 55.00%
  6. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 11 people, 55.00%
  7. Insomnia (sleeplessness): 11 people, 55.00%
  8. Cough: 8 people, 40.00%
  9. Back Pain: 5 people, 25.00%
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 5 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Trichlormethiazide and Repaglinide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Trichlormethiazide and Repaglinide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trichlormethiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Repaglinide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trichlormethiazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Repaglinide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on trichlormethiazide and repaglinide (the active ingredients of Trichlormethiazide and Repaglinide, respectively), and Trichlormethiazide and Repaglinide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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