Tricor and Questran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tricor (fenofibrate) and Questran (cholestyramine). Common drug interactions include dehydration among females and myalgia among males.

The phase IV clinical study analyzes what interactions people have when they take Tricor and Questran. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Tricor?

Tricor has active ingredients of fenofibrate. It is often used in high blood cholesterol. eHealthMe is studying from 22,641 Tricor users. Check the latest studies of Tricor.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.



On Jul, 26, 2026

45 people who take Tricor and Questran together, and have interactions are studied.

Tricor and Questran drug interactions.

What are the common drug interactions of Tricor and Questran, by gender? *:

female:

  1. Dehydration (dryness resulting from the removal of water)
  2. Gastroenteritis (inflammation of stomach and intestine)
  3. Haemoglobin decreased
  4. Hyperglycaemia (high blood sugar)
  5. Hypokalaemia (low potassium)
  6. Malignant melanoma (skin cancer rises from melancytes)
  7. Nephrolithiasis (calculi in the kidneys)
  8. Renal failure acute (rapid kidney dysfunction)
  9. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  10. Abdominal adhesions (inflammation of abdomen)

male:

  1. Myalgia (muscle pain)
  2. Oedema (fluid collection in tissue)
  3. Joint stiffness
  4. Keratoacanthoma (a common low-grade (unlikely to metastasize or invade) skin tumour that is believed to originate from the neck of the hair follicle)
  5. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  6. Pain
  7. Pain in extremity
  8. Rash papular (redness with papule)
  9. Rash pruritic (redness with itching)
  10. Scar

What are the common drug interactions of Tricor and Questran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abdominal pain
  2. Cholecystitis chronic (long lasting infection of gallbladder)
  3. Constipation
  4. Dyspepsia (indigestion)
  5. Gallbladder disorder
  6. Gallbladder injury
  7. Incision site pain
  8. Nausea (feeling of having an urge to vomit)

30-39:

  1. Abdominal pain upper
  2. Alcoholic pancreatitis
  3. Back injury
  4. Death
  5. Fatigue (feeling of tiredness)
  6. Injection site erythema (redness at injection site)
  7. Injection site mass
  8. Injection site pain
  9. Injection site pruritus (severe itching at injection site)
  10. Myalgia (muscle pain)

40-49:

  1. Alcoholic pancreatitis
  2. Anxiety
  3. Back pain
  4. Chest pain
  5. Dizziness
  6. Hyperhidrosis (abnormally increased sweating)
  7. Hypersensitivity
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Myalgia (muscle pain)
  10. Oedema (fluid collection in tissue)

50-59:

  1. Dyspnoea (difficult or laboured respiration)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Hyperlipidaemia (presence of excess lipids in the blood)
  4. Abdominal adhesions (inflammation of abdomen)
  5. Abdominal pain upper
  6. Adnexa uteri mass (ovarian cysts)
  7. Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)
  8. Angina pectoris (chest pain due to ischemia of the heart muscle)
  9. Anxiety
  10. Aortic valve incompetence

60+:

  1. Cyst (a closed sac)
  2. Keratoacanthoma (a common low-grade (unlikely to metastasize or invade) skin tumour that is believed to originate from the neck of the hair follicle)
  3. Fatigue (feeling of tiredness)
  4. Gastroenteritis (inflammation of stomach and intestine)
  5. Haemoglobin decreased
  6. Hypokalaemia (low potassium)
  7. Malignant melanoma (skin cancer rises from melancytes)
  8. Nephrolithiasis (calculi in the kidneys)
  9. Oropharyngeal pain
  10. Pain in extremity

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 14 people, 31.11%
  2. High Blood Pressure: 7 people, 15.56%
  3. Type 2 Diabetes: 5 people, 11.11%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 8.89%
  5. Peripheral Sensory Neuropathy (damage to one or more of your peripheral nerves): 3 people, 6.67%
  6. Inflammatory Bowel Disease: 3 people, 6.67%
  7. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 6.67%
  8. Dyslipidaemia (abnormal amount of lipids): 3 people, 6.67%
  9. Chronic Kidney Disease: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Tricor and Questran?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tricor and Questran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tricor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Questran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tricor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Questran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fenofibrate and cholestyramine (the active ingredients of Tricor and Questran, respectively), and Tricor and Questran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: