Trikafta and Vancomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trikafta (elexacaftor, ivacaftor, tezacaftor; ivacaftor) and Vancomycin (vancomycin). Common drug interactions include abdominal distension among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Trikafta and Vancomycin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Trikafta?

Trikafta has active ingredients of elexacaftor, ivacaftor, tezacaftor; ivacaftor. eHealthMe is studying from 11,852 Trikafta users. Check the latest studies of Trikafta.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.



On Jul, 10, 2026

19 people who take Trikafta and Vancomycin together, and have interactions are studied.

Trikafta and Vancomycin drug interactions.

What are the common drug interactions of Trikafta and Vancomycin, by gender? *:

female:

  1. Abdominal distension
  2. Weight increased
  3. Alopecia (absence of hair from areas of the body)
  4. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  5. Anger
  6. Blood glucose decreased
  7. Emotional poverty
  8. Heart rate increased
  9. Hepatic enzyme increased
  10. Increased appetite

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Pain in extremity
  3. Joint injury
  4. Sleep disorder
  5. Thyroid disorder (thyroid diseases)
  6. Abdominal distension
  7. Abdominal pain upper
  8. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  9. Arthralgia (joint pain)
  10. Back pain

What are the common drug interactions of Trikafta and Vancomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal pain upper
  2. Cough
  3. Diarrhoea

20-29:

  1. Respiratory disorder (respiratory disease)
  2. Abdominal pain
  3. Cystic fibrosis (disease of the secretary glands)
  4. Paranasal sinus hypersecretion

30-39:

  1. Fatigue (feeling of tiredness)
  2. Abdominal distension
  3. Headache (pain in head)
  4. Abdominal pain upper
  5. Diarrhoea
  6. Dyspnoea (difficult or laboured respiration)
  7. Haematochezia (passage of stools containing blood)
  8. Haemorrhage (bleeding)
  9. Nephrolithiasis (calculi in the kidneys)
  10. Weight increased

40-49:

n/a

50-59:

n/a

60+:

  1. Drug eruption (adverse drug reaction of the skin)
  2. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  3. Nausea (feeling of having an urge to vomit)
  4. Pain in extremity
  5. Sleep disorder
  6. Thyroid disorder (thyroid diseases)
  7. Weight increased
  8. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  9. Pericarditis (inflammation of the pericardium)
  10. Cellulitis (infection under the skin)

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 17 people, 89.47%
  2. Cystic Fibrosis Lung (fibrosis with cyst in the lung): 2 people, 10.53%
  3. Stress And Anxiety: 1 person, 5.26%
  4. Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 1 person, 5.26%
  5. Infection: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Trikafta and Vancomycin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Trikafta and Vancomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trikafta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vancomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trikafta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on elexacaftor, ivacaftor, tezacaftor; ivacaftor and vancomycin (the active ingredients of Trikafta and Vancomycin, respectively), and Trikafta and Vancomycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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