Trilafon and Baclofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trilafon (perphenazine) and Baclofen (baclofen). Common drug interactions include diarrhoea among females and arteriosclerosis among males.

The phase IV clinical study analyzes what interactions people have when they take Trilafon and Baclofen. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Trilafon?

Trilafon has active ingredients of perphenazine. It is often used in bipolar disorder. eHealthMe is studying from 1,448 Trilafon users. Check the latest studies of Trilafon.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

On Jul, 13, 2026

27 people who take Trilafon and Baclofen together, and have interactions are studied.

Trilafon and Baclofen drug interactions.

What are the common drug interactions of Trilafon and Baclofen, by gender? *:

female:

Diarrhoea
Headache (pain in head)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Poor venous access
Vomiting
Weight decreased
Chills (felling of cold)
Diarrhoea haemorrhagic (bloody diarrhoea)
Infusion related reaction

male:

Arteriosclerosis (thickening and hardening of arteries)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Hemiparesis (weakness on one side of the body)
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Migraine (headache)
Sleep disorder
Therapeutic response unexpected

What are the common drug interactions of Trilafon and Baclofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Road traffic accident
Brain injury
Diarrhoea
Memory impairment
Nausea (feeling of having an urge to vomit)
Poor venous access
Vomiting
Weight decreased
Chills (felling of cold)
Diarrhoea haemorrhagic (bloody diarrhoea)

40-49:

n/a

50-59:

Activities of daily living impaired
Fatigue (feeling of tiredness)
Memory impairment
Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

Arteriosclerosis (thickening and hardening of arteries)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cough
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Fall
Grunting (abnormal, short, deep, hoarse sounds in exhalation that often accompany severe chest pain)
Headache (pain in head)
Insomnia (sleeplessness)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 16 people, 59.26%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 16 people, 59.26%
Nausea (feeling of having an urge to vomit): 14 people, 51.85%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.41%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 7.41%
High Blood Cholesterol: 2 people, 7.41%
Depression: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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