Trileptal and Codeine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Trileptal (oxcarbazepine) and Codeine (codeine sulfate). Common drug interactions include drug hypersensitivity among females and rash among males.
The phase IV clinical study analyzes what interactions people have when they take Trileptal and Codeine. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.
What is Trileptal?
Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.
What is Codeine?
Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.
30 people who take Trileptal and Codeine together, and have interactions are studied.

What are the common drug interactions of Trileptal and Codeine, by gender? *:
female:
- Drug hypersensitivity
- Headache (pain in head)
- Pruritus (severe itching of the skin)
- Restlessness (not able to rest)
- Road traffic accident
- Anaphylactic reaction (serious allergic reaction)
- Agitation (state of anxiety or nervous excitement)
- Anxiety
- Aphasia (damage to the parts of the brain that control language)
- Balance disorder
male:
- Rash
What are the common drug interactions of Trileptal and Codeine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anaphylactic reaction (serious allergic reaction)
- Dyspnoea (difficult or laboured respiration)
- Oxygen saturation decreased
- Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
- Throat irritation
- Urticaria (rash of round, red welts on the skin that itch intensely)
40-49:
- Urinary retention (the inability to completely or partially empty the bladder)
- Vision blurred
- Visual impairment
- Vomiting
- Dysphagia (a condition in which swallowing is difficult or painful)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Diarrhoea
- Dizziness
- Dyspnoea (difficult or laboured respiration)
50-59:
- Tooth extraction
- Drug hypersensitivity
- Drug intolerance (drug sensitivity)
- Dizziness
60+:
- Drug hypersensitivity
- Depressed mood
- Drug ineffective
- Fear
- Neck injury
- Road traffic accident
- Vitamin d decreased
What are the existing conditions these people have? *
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 10.00%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 6.67%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 6.67%
- Depression: 2 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Trileptal and Codeine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Trileptal and Codeine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Trileptal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Codeine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trileptal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Codeine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on oxcarbazepine and codeine sulfate (the active ingredients of Trileptal and Codeine, respectively), and Trileptal and Codeine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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