Trileptal and Gentamicin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trileptal (oxcarbazepine) and Gentamicin (gentamicin sulfate). Common drug interactions include renal failure among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Trileptal and Gentamicin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Trileptal?

Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.

What is Gentamicin?

Gentamicin has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 21,654 Gentamicin users. Check the latest studies of Gentamicin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

19 people who take Trileptal and Gentamicin together, and have interactions are studied.

Trileptal and Gentamicin drug interactions.

What are the common drug interactions of Trileptal and Gentamicin, by gender? *:

female:

Renal failure (kidney dysfunction)
Abdominal pain
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Vomiting

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Dry mouth
Eosinophil count increased
Haematuria (presence of blood in urine)
Hepatic failure (liver failure)
Hepatitis (inflammation of the liver)
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Trileptal and Gentamicin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Electrocardiogram qt prolonged
Acne cystic (skin problems that cause pimples)
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Bradycardia (abnormally slow heart action)
Conductive deafness (deafness due to a problem in conducting sound waves)
Dry mouth
Hypotension (abnormally low blood pressure)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pancreatitis acute (sudden inflammation of pancreas)
Rash

20-29:

n/a

30-39:

n/a

40-49:

Renal failure (kidney dysfunction)
Abdominal pain
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Vomiting

50-59:

Eosinophilia (eosinophil count in the peripheral blood exceeds)
Hepatitis (inflammation of the liver)
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Renal failure (kidney dysfunction)

60+:

Chronic kidney disease
Alanine aminotransferase increased
Hepatic failure (liver failure)
Lung infection pseudomonal (bacterial infection of lung by pseudomonas aeruginosa)
Multi-organ failure (multisystem organ failure)
Nephrogenic anaemia (anaemia due to kidney disease)
Pyrexia (fever)
Rash macular (small, flat red spots)
Rash morbilliform (a rash that looks like measles)
Rash papular (redness with papule)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 31.58%
Multiple Allergies (allergy to multiple agents): 3 people, 15.79%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 15.79%
Pain: 3 people, 15.79%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 15.79%
Bladder Pain: 2 people, 10.53%
Constipation: 2 people, 10.53%
Cough: 2 people, 10.53%
Gait Disturbance: 2 people, 10.53%
Gout (uric acid crystals building up in the body): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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