Trimethoprim and Atrovent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trimethoprim (trimethoprim) and Atrovent (ipratropium bromide). Common drug interactions include cerumen impaction among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Trimethoprim and Atrovent. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Trimethoprim?

Trimethoprim has active ingredients of trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 8,213 Trimethoprim users. Check the latest studies of Trimethoprim.

What is Atrovent?

Atrovent has active ingredients of ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 33,210 Atrovent users. Check the latest studies of Atrovent.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

34 people who take Trimethoprim and Atrovent together, and have interactions are studied.

Trimethoprim and Atrovent drug interactions.

What are the common drug interactions of Trimethoprim and Atrovent, by gender? *:

female:

Cerumen impaction
Chest discomfort
Chest pain
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Chorea (abnormal involuntary movement disorder)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Confusional state
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Anaemia (lack of blood)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

male:

Abdominal distension
Device dislocation
Chest pain
Coma (state of unconsciousness lasting more than six hours)
Cough
Drug effect prolonged
Dyspnoea (difficult or laboured respiration)
Lower respiratory tract infection
Pneumonia
Septicaemia staphylococcal (blood infection with bacteria)

What are the common drug interactions of Trimethoprim and Atrovent, by age (0-1 to 60+)? *:

0-1:

Loose stools
Skin candida (fungal infection of skin)

2-9:

Device dislocation
Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
Weight gain poor

10-19:

Abdominal distension
Abdominal pain

20-29:

n/a

30-39:

Body height decreased
Breast cancer
Discomfort
Drug ineffective
Dysphonia (speech disorder attributable to a disorder of phonation)
Headache (pain in head)
Hip fracture
Lower limb fracture
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Migraine (headache)

40-49:

Cough
Decreased appetite
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Abdominal pain
Abdominal pain upper
Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
Anxiety
Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
Arthralgia (joint pain)
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)

50-59:

Blood culture positive
Drug toxicity
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Impaired gastric emptying
Lower respiratory tract infection
Septicaemia staphylococcal (blood infection with bacteria)
Staphylococcal infection (an infection with staphylococcus bacteria)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Anaemia (lack of blood)

60+:

Confusional state
Sepsis (a severe blood infection that can lead to organ failure and death)
Hip fracture
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Respiratory distress (difficulty in breathing)
Acidosis (build-up of carbon dioxide in the blood)
Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Anaemia (lack of blood)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)

What are the existing conditions these people have? *

Pain: 7 people, 20.59%
Depression: 6 people, 17.65%
Abdominal Pain: 5 people, 14.71%
Infection: 5 people, 14.71%
Respiratory Disorder (respiratory disease): 4 people, 11.76%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 4 people, 11.76%
Stress And Anxiety: 4 people, 11.76%
Headache (pain in head): 3 people, 8.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.82%
Bladder Disorder: 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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