Trimethoprim and Haloperidol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trimethoprim (trimethoprim) and Haloperidol (haloperidol). Common drug interactions include peripheral swelling among females and device dislocation among males.

The phase IV clinical study analyzes what interactions people have when they take Trimethoprim and Haloperidol. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Trimethoprim?

Trimethoprim has active ingredients of trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 8,213 Trimethoprim users. Check the latest studies of Trimethoprim.

What is Haloperidol?

Haloperidol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 16,637 Haloperidol users. Check the latest studies of Haloperidol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

79 people who take Trimethoprim and Haloperidol together, and have interactions are studied.

Trimethoprim and Haloperidol drug interactions.

What are the common drug interactions of Trimethoprim and Haloperidol, by gender? *:

female:

Peripheral swelling
Rhinorrhoea (watery mucus discharge from the nose)
Haematemesis (vomiting of blood)
Migraine (headache)
Oesophageal ulcer (ulcer of oesophagus)
Reflux oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus)
Conjunctivitis (pink eye)
Oral candidiasis (fungal infection of mouth)
Rectal haemorrhage (bleeding from anus)
Vulvovaginal candidiasis (vulvovaginal infection by fungi)

male:

Device dislocation
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Cheyne-stokes respiration (abnormal pattern of breathing combination of slow and faster)
Dyskinesia (abnormality or impairment of voluntary movement)
Electrolyte imbalance
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Muscular weakness (muscle weakness)
Pulseless electrical activity
Pyrexia (fever)

What are the common drug interactions of Trimethoprim and Haloperidol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Device dislocation
Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
Weight gain poor
Lower respiratory tract infection

10-19:

n/a

20-29:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

30-39:

Abdominal pain
Vomiting
Diarrhoea
Nausea (feeling of having an urge to vomit)
Headache (pain in head)
Back pain
Fatigue (feeling of tiredness)
Pain
Viral infection
Alanine aminotransferase increased

40-49:

Insomnia (sleeplessness)
Neuropathy peripheral (surface nerve damage)
Conjunctivitis (pink eye)
Nausea (feeling of having an urge to vomit)
Oral candidiasis (fungal infection of mouth)
Rectal haemorrhage (bleeding from anus)
Vulvovaginal candidiasis (vulvovaginal infection by fungi)
Abnormal sensation in eye
Asthenia (weakness)
Decreased appetite

50-59:

Catatonia (unresponsive to external stimuli)
Delirium (wild excitement)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased
White blood cell count decreased

60+:

Haematemesis (vomiting of blood)
Oesophageal ulcer (ulcer of oesophagus)
Pain
Parkinson's disease
Septic shock (shock due to blood infection)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Agonal rhythm (an idioventricular rhythm, characterized by unusually wide and bizarre ventricular complexes)
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Cheyne-stokes respiration (abnormal pattern of breathing combination of slow and faster)
Death

What are the existing conditions these people have? *

Pain: 23 people, 29.11%
Breast Cancer: 10 people, 12.66%
Constipation: 10 people, 12.66%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 12.66%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 10 people, 12.66%
High Blood Cholesterol: 9 people, 11.39%
Infection: 8 people, 10.13%
Breast Cancer Metastatic: 8 people, 10.13%
Hallucinations (sensations that appear real but are created by your mind): 7 people, 8.86%
Agitation (state of anxiety or nervous excitement): 7 people, 8.86%

* Approximation only. Some reports may have incomplete information.

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