Trimethoprim and Inspra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Trimethoprim (trimethoprim) and Inspra (eplerenone). Common drug interactions include rectal abscess among males.
The phase IV clinical study analyzes what interactions people have when they take Trimethoprim and Inspra. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Trimethoprim?
Trimethoprim has active ingredients of trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 8,213 Trimethoprim users. Check the latest studies of Trimethoprim.
What is Inspra?
Inspra has active ingredients of eplerenone. It is often used in high blood pressure. eHealthMe is studying from 3,510 Inspra users. Check the latest studies of Inspra.
16 people who take Trimethoprim and Inspra together, and have interactions are studied.

What are the common drug interactions of Trimethoprim and Inspra, by gender? *:
female:
n/a
male:
- Rectal abscess (pus in rectum)
- Proctalgia (pain in the rectum)
- Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
What are the common drug interactions of Trimethoprim and Inspra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Rectal abscess (pus in rectum)
- Proctalgia (pain in the rectum)
- Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
What are the existing conditions these people have? *
- Cardiac Amyloidosis (protein deposition in heart): 16 people, 100.00%
- Primary Amyloidosis (disease that occurs when substances called amyloid proteins build up in your organs): 2 people, 12.50%
* Approximation only. Some reports may have incomplete information.
Do you take Trimethoprim and Inspra?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Trimethoprim (8,213 reports)
- Inspra (3,510 reports)
Browse all drug interactions of Trimethoprim and Inspra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Trimethoprim:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Inspra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trimethoprim and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Inspra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on trimethoprim and eplerenone (the active ingredients of Trimethoprim and Inspra, respectively), and Trimethoprim and Inspra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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