Trimethoprim and Ocrevus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trimethoprim (trimethoprim) and Ocrevus (ocrelizumab). Common drug interactions include malignant melanoma among females and malaise among males.

The phase IV clinical study analyzes what interactions people have when they take Trimethoprim and Ocrevus. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Trimethoprim?

Trimethoprim has active ingredients of trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 8,213 Trimethoprim users. Check the latest studies of Trimethoprim.

What is Ocrevus?

Ocrevus has active ingredients of ocrelizumab. eHealthMe is studying from 56,583 Ocrevus users. Check the latest studies of Ocrevus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

12 people who take Trimethoprim and Ocrevus together, and have interactions are studied.

Trimethoprim and Ocrevus drug interactions.

What are the common drug interactions of Trimethoprim and Ocrevus, by gender? *:

female:

Malignant melanoma (skin cancer rises from melancytes)
Pain
Asthenia (weakness)
Cd8 lymphocytes decreased
Lung neoplasm malignant (cancer tumour of lung)
Lymphocyte count decreased
Nerve injury
Salivary gland cancer
Salivary gland neoplasm (tumour of salivary gland)
Urticaria (rash of round, red welts on the skin that itch intensely)

male:

Malaise (a feeling of general discomfort or uneasiness)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Pneumonia
Rash
Vision blurred
Visual acuity reduced (reduced clearness of vision)
Abscess (pus)
B-lymphocyte count decreased
Diplopia (double vision)

What are the common drug interactions of Trimethoprim and Ocrevus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Kidney infection

40-49:

Asthenia (weakness)
Bedridden
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Visual impairment

50-59:

Abscess (pus)
Dehydration (dryness resulting from the removal of water)
Memory impairment
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Pneumonia
Syncope (loss of consciousness with an inability to maintain postural tone)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

60+:

Malignant melanoma (skin cancer rises from melancytes)
Pain
Asthenia (weakness)
Influenza
Malaise (a feeling of general discomfort or uneasiness)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscle spasms (muscle contraction)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Myelitis transverse (a neurological condition consisting of an inflammatory process of the spinal cord)
Oropharyngeal pain

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 33.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 25.00%
High Blood Cholesterol: 3 people, 25.00%
Pain: 2 people, 16.67%
Neuralgia (pain in one or more nerves): 2 people, 16.67%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 1 person, 8.33%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 8.33%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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