Trintellix and Advil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trintellix (vortioxetine hydrobromide) and Advil (ibuprofen). Common drug interactions include anxiety disorder among females and dyskinesia among males.

The phase IV clinical study analyzes what interactions people have when they take Trintellix and Advil. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.

On Jul, 13, 2026

60 people who take Trintellix and Advil together, and have interactions are studied.

What are the common drug interactions of Trintellix and Advil, by gender? *:

female:

Anxiety disorder
Back pain
Balance disorder
Blood cholesterol decreased
Body dysmorphic disorder (type of mental illness)
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Disturbance in attention
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)

male:

Dyskinesia (abnormality or impairment of voluntary movement)
Abdominal discomfort
Fatigue (feeling of tiredness)
Food poisoning (poison in food)
Hypersomnia (excessive daytime sleepiness (eds))
Inflammation
Joint injury
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)

What are the common drug interactions of Trintellix and Advil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Nausea (feeling of having an urge to vomit)
Vomiting
Anxiety disorder
Back pain
Blood cholesterol decreased
Body dysmorphic disorder (type of mental illness)
Constipation
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Disturbance in attention

30-39:

Dizziness
Nausea (feeling of having an urge to vomit)
Drug ineffective
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Throat tightness
Urticaria (rash of round, red welts on the skin that itch intensely)
Vision blurred

40-49:

n/a

50-59:

Fatigue (feeling of tiredness)
Alcohol abuse
Loss of consciousness
Self esteem decreased (self worth reduced)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Infusion related reaction
Suicidal ideation
Weight increased
Asthenia (weakness)
Burning mouth syndrome (pain in the mouth and burning sensation on tongue)

60+:

Pruritus (severe itching of the skin)
Fatigue (feeling of tiredness)
Dizziness
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hyperhidrosis (abnormally increased sweating)
Hypersensitivity
Hypertension (high blood pressure)
Infection
Irritability
Large intestine perforation (hole in large intestine)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 25 people, 41.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 22 people, 36.67%
Stress And Anxiety: 10 people, 16.67%
Drowsiness: 7 people, 11.67%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 6.67%
Primary Immunodeficiency Syndrome: 3 people, 5.00%
Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 5.00%
Immunodeficiency Common Variable: 3 people, 5.00%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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