Trintellix and Aubagio drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Trintellix (vortioxetine hydrobromide) and Aubagio (teriflunomide). Common drug interactions include fatigue among females and alopecia among males.
The phase IV clinical study analyzes what interactions people have when they take Trintellix and Aubagio. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.
What is Trintellix?
Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.
What is Aubagio?
Aubagio has active ingredients of teriflunomide. It is often used in multiple sclerosis. eHealthMe is studying from 50,041 Aubagio users. Check the latest studies of Aubagio.
37 people who take Trintellix and Aubagio together, and have interactions are studied.

What are the common drug interactions of Trintellix and Aubagio, by gender? *:
female:
- Fatigue (feeling of tiredness)
- Memory impairment
- Feeling hot
- Headache (pain in head)
- Anxiety
- Arthralgia (joint pain)
- Pain
- Arthropathy
- Gait disturbance
- Hypoaesthesia (reduced sense of touch or sensation)
male:
- Alopecia (absence of hair from areas of the body)
- Drug ineffective
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Overdose
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
What are the common drug interactions of Trintellix and Aubagio, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Nausea (feeling of having an urge to vomit)
- Alopecia (absence of hair from areas of the body)
- Drug ineffective
- Malaise (a feeling of general discomfort or uneasiness)
- Overdose
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Blood pressure increased
- Chest pain
- Headache (pain in head)
- Hypoaesthesia (reduced sense of touch or sensation)
40-49:
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Aphasia (damage to the parts of the brain that control language)
- Nausea (feeling of having an urge to vomit)
- Weight decreased
50-59:
- Anxiety
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Feeling hot
- Nausea (feeling of having an urge to vomit)
- Arthralgia (joint pain)
- Cough
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Pain
- Rash
60+:
- Alopecia (absence of hair from areas of the body)
- Fatigue (feeling of tiredness)
- Depressed mood
- Fall
- Hypoaesthesia (reduced sense of touch or sensation)
- Memory impairment
- Muscle disorder (muscle disease)
- Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
- Muscular weakness (muscle weakness)
- Pain in extremity
What are the existing conditions these people have? *
- Vitamin D Decreased: 2 people, 5.41%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.41%
- Bipolar Disorder (mood disorder): 2 people, 5.41%
* Approximation only. Some reports may have incomplete information.
Do you take Trintellix and Aubagio?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Trintellix (13,067 reports)
- Aubagio (50,041 reports)
Browse all drug interactions of Trintellix and Aubagio:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Trintellix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Aubagio:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trintellix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aubagio and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on vortioxetine hydrobromide and teriflunomide (the active ingredients of Trintellix and Aubagio, respectively), and Trintellix and Aubagio (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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