Trintellix and Cozaar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trintellix (vortioxetine hydrobromide) and Cozaar (losartan potassium). Common drug interactions include dizziness among females and gastrooesophageal reflux disease among males.

The phase IV clinical study analyzes what interactions people have when they take Trintellix and Cozaar. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

On Aug, 08, 2026

26 people who take Trintellix and Cozaar together, and have interactions are studied.

Trintellix and Cozaar drug interactions.

What are the common drug interactions of Trintellix and Cozaar, by gender? *:

female:

Dizziness
Fatigue (feeling of tiredness)
Alopecia (absence of hair from areas of the body)
Back pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Pruritus (severe itching of the skin)
Dehydration (dryness resulting from the removal of water)
Hypotension (abnormally low blood pressure)
Renal impairment (severely reduced kidney function)
Urinary retention (the inability to completely or partially empty the bladder)

male:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Malignant melanoma (skin cancer rises from melancytes)
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Necrosis (the death of body tissue)
Oesophagitis (inflammation of oesophagus)
Self esteem decreased (self worth reduced)
Aphasia (damage to the parts of the brain that control language)
Memory impairment
Sleep disorder
Back pain

What are the common drug interactions of Trintellix and Cozaar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dizziness
Fatigue (feeling of tiredness)
Dehydration (dryness resulting from the removal of water)
Hypotension (abnormally low blood pressure)
Renal impairment (severely reduced kidney function)
Urinary retention (the inability to completely or partially empty the bladder)
Ventricular extrasystoles (premature cardiac contraction)
Back pain
Dyspnoea (difficult or laboured respiration)
Gastroenteritis clostridial (inflammation of stomach and intestine clostridial)

50-59:

Alopecia (absence of hair from areas of the body)
Back pain
Nausea (feeling of having an urge to vomit)
Vomiting

60+:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Loss of consciousness
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Necrosis (the death of body tissue)
Oesophagitis (inflammation of oesophagus)
Pruritus (severe itching of the skin)
Self esteem decreased (self worth reduced)
Activation syndrome (suicidal or homicidal stimulation or agitation)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Back pain

What are the existing conditions these people have? *

Pain: 3 people, 11.54%
High Blood Cholesterol: 3 people, 11.54%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.54%
Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 11.54%
Sleep Disorder: 2 people, 7.69%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.69%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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