Trintellix and Luvox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trintellix (vortioxetine hydrobromide) and Luvox (fluvoxamine maleate). Common drug interactions include suicidal ideation among females and depressed mood among males.

The phase IV clinical study analyzes what interactions people have when they take Trintellix and Luvox. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.

What is Luvox?

Luvox has active ingredients of fluvoxamine maleate. It is often used in obsessive-compulsive disorder. eHealthMe is studying from 13,439 Luvox users. Check the latest studies of Luvox.

On Jul, 20, 2026

25 people who take Trintellix and Luvox together, and have interactions are studied.

What are the common drug interactions of Trintellix and Luvox, by gender? *:

female:

Suicidal ideation
Abdominal discomfort
Agitation (state of anxiety or nervous excitement)
Anger
Blood pressure increased
Mydriasis (a dilation of the pupil)
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Pyrexia (fever)
Rash
Tremor (trembling or shaking movements in one or more parts of your body)

male:

Depressed mood
Intentional self-injury
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Nausea (feeling of having an urge to vomit)
Tremor (trembling or shaking movements in one or more parts of your body)
Suicide attempt
Pruritus generalised (generalized itching)
Benign prostatic hyperplasia (benign enlargement of the prostate)

What are the common drug interactions of Trintellix and Luvox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pruritus generalised (generalized itching)

20-29:

Depressed mood
Intentional self-injury
Suicide attempt

30-39:

Blood glucose increased
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Nausea (feeling of having an urge to vomit)
Tremor (trembling or shaking movements in one or more parts of your body)

40-49:

Abdominal discomfort
Agitation (state of anxiety or nervous excitement)
Anger
Blood pressure increased
Mydriasis (a dilation of the pupil)
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Pyrexia (fever)
Rash
Suicidal ideation
Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

Hypertension (high blood pressure)
Obesity (having too much body fat)
Therapeutic response unexpected
Weight decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Benign prostatic hyperplasia (benign enlargement of the prostate)

60+:

Cardiomyopathy (weakening of the heart muscle)
Constipation
Dizziness
Drug ineffective
Nausea (feeling of having an urge to vomit)
Arrhythmia (irregular heartbeat)
Fall
Myocarditis (inflammation of heart muscle myocardium)
Upper limb fracture

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 28.00%
Stress And Anxiety: 6 people, 24.00%
Panic Disorder: 4 people, 16.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 16.00%
Nausea (feeling of having an urge to vomit): 2 people, 8.00%
Migraine (headache): 2 people, 8.00%
Drowsiness: 2 people, 8.00%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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