Trintellix and Mirapex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trintellix (vortioxetine hydrobromide) and Mirapex (pramipexole dihydrochloride). Common drug interactions include emergency care among females and back disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Trintellix and Mirapex. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.

What is Mirapex?

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 20,622 Mirapex users. Check the latest studies of Mirapex.

On Jul, 18, 2026

67 people who take Trintellix and Mirapex together, and have interactions are studied.

Trintellix and Mirapex drug interactions.

What are the common drug interactions of Trintellix and Mirapex, by gender? *:

female:

Emergency care
Feeling jittery
Fluid retention (an abnormal accumulation of fluid in the blood)
Hepatic adenoma (benign liver tumour)
Hyperhidrosis (abnormally increased sweating)
Incontinence (lack of moderation or self-control)
Injection site erythema (redness at injection site)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Pain
Memory impairment

male:

Back disorder
Rash
Drug hypersensitivity
Drug ineffective
Fall
Fatigue (feeling of tiredness)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Irritable bowel syndrome
Memory impairment
Obesity (having too much body fat)

What are the common drug interactions of Trintellix and Mirapex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug ineffective
Disease recurrence

40-49:

Hospitalisation
Gallbladder operation
Diplopia (double vision)
Pain
Poor quality sleep
Retinal vascular disorder (a range of eye diseases that affect the blood vessels in the eye)
Cystitis (inflammation of the wall of the bladder)
Memory impairment
Spinal fusion surgery
Hysterectomy

50-59:

Abdominal pain
Anaemia (lack of blood)
Anxiety
Back disorder
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Carditis (infection of heart and surrounding)
Chest pain
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Insomnia (sleeplessness)

60+:

Pain in extremity
Abdominal discomfort
Haematemesis (vomiting of blood)
Hyperhidrosis (abnormally increased sweating)
Infusion related reaction
Platelet count decreased
Pneumonia
Psychotic disorder
Respiratory tract infection
Sinusitis (inflammation of sinus)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 30 people, 44.78%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 16 people, 23.88%
Immunodeficiency: 9 people, 13.43%
Drowsiness: 6 people, 8.96%
Insomnia (sleeplessness): 5 people, 7.46%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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