Trintellix and Nuvaring drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trintellix (vortioxetine hydrobromide) and Nuvaring (ethinyl estradiol; etonogestrel). Common drug interactions include pancreatitis among females.

The phase IV clinical study analyzes what interactions people have when they take Trintellix and Nuvaring. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.

What is Nuvaring?

Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,730 Nuvaring users. Check the latest studies of Nuvaring.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 14, 2026

11 people who take Trintellix and Nuvaring together, and have interactions are studied.

Trintellix and Nuvaring drug interactions.

What are the common drug interactions of Trintellix and Nuvaring, by gender? *:

female:

Pancreatitis (inflammation of pancreas)
Appetite disorder (abnormal eating habits)
Pelvic pain
Vaginal haemorrhage (vaginal bleeding)
Vaginal infection
Influenza like illness
Insomnia (sleeplessness)
Libido decreased (loss of interest in sex)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Menstrual disorder (disease of menstrual cycle)

male:

n/a

What are the common drug interactions of Trintellix and Nuvaring, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Libido decreased (loss of interest in sex)
Ovarian cyst (fluid filled sac of the ovary)
Pelvic pain

30-39:

Pancreatitis (inflammation of pancreas)
Appetite disorder (abnormal eating habits)
Influenza like illness
Insomnia (sleeplessness)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Menstrual disorder (disease of menstrual cycle)
Vaginal haemorrhage (vaginal bleeding)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 36.36%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 27.27%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 18.18%
Stress And Anxiety: 1 person, 9.09%
Menstrual Disorder (disease of menstrual cycle): 1 person, 9.09%
Insomnia (sleeplessness): 1 person, 9.09%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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