Triumeq and Odefsey drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Triumeq (abacavir sulfate; dolutegravir sodium; lamivudine) and Odefsey (emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate). Common drug interactions include tremor among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Triumeq and Odefsey. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Triumeq?

Triumeq has active ingredients of abacavir sulfate; dolutegravir sodium; lamivudine. It is often used in hiv infection. eHealthMe is studying from 6,900 Triumeq users. Check the latest studies of Triumeq.

What is Odefsey?

Odefsey has active ingredients of emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 4,605 Odefsey users. Check the latest studies of Odefsey.



On Aug, 03, 2026

61 people who take Triumeq and Odefsey together, and have interactions are studied.

Triumeq and Odefsey drug interactions.

What are the common drug interactions of Triumeq and Odefsey, by gender? *:

female:

  1. Tremor (trembling or shaking movements in one or more parts of your body)
  2. Acute myocardial infarction (acute heart attack)
  3. Blood creatinine increased
  4. Bone density decreased
  5. Limb injury
  6. Emotional distress
  7. Pain
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Anxiety
  10. Osteoporosis (bones weak and more likely to break)

male:

  1. Anxiety
  2. Pain
  3. Bone density decreased
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Diarrhoea
  6. Tooth loss
  7. Asthenia (weakness)
  8. Decreased activity
  9. Hip arthroplasty
  10. Blood creatinine increased

What are the common drug interactions of Triumeq and Odefsey, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Completed suicide (act of taking one's own life)
  2. Joint stiffness
  3. Renal failure (kidney dysfunction)
  4. Vitamin d deficiency
  5. Anxiety
  6. Blood creatinine increased
  7. Chronic kidney disease
  8. Emotional distress
  9. Insomnia (sleeplessness)
  10. Intervertebral disc protrusion (spinal disc protrusion)

30-39:

  1. Fatigue (feeling of tiredness)
  2. Depression
  3. Renal impairment (severely reduced kidney function)
  4. Decreased activity
  5. Diarrhoea
  6. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  7. Quality of life decreased
  8. Disturbance in attention
  9. Hyperkalaemia (damage to or disease of the kidney)
  10. Hypertension (high blood pressure)

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Pain
  5. Bone density decreased
  6. Chronic kidney disease
  7. Hip arthroplasty
  8. Osteoporosis (bones weak and more likely to break)
  9. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  10. Osteopenia (a condition where bone mineral density is lower than normal)

50-59:

  1. Chronic kidney disease
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Emotional distress
  5. Pain
  6. Osteoporosis (bones weak and more likely to break)
  7. Depression
  8. Renal impairment (severely reduced kidney function)
  9. Tooth loss
  10. Multiple injuries

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Bone loss
  4. Depressed mood
  5. Depression
  6. Drug intolerance (drug sensitivity)
  7. Fall
  8. Fear
  9. Gait disturbance
  10. General physical health deterioration (weak health status)

What are the existing conditions these people have? *

  1. Pain: 7 people, 11.48%
  2. Depression: 6 people, 9.84%
  3. Constipation: 5 people, 8.20%
  4. Bacterial Infection: 5 people, 8.20%
  5. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 4 people, 6.56%
  6. Inflammation: 4 people, 6.56%
  7. Erection Problems: 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

Do you take Triumeq and Odefsey?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Triumeq and Odefsey:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Triumeq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Odefsey:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Triumeq and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Odefsey and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on abacavir sulfate; dolutegravir sodium; lamivudine and emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate (the active ingredients of Triumeq and Odefsey, respectively), and Triumeq and Odefsey (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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