Trizivir and Imodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trizivir (abacavir sulfate; lamivudine; zidovudine) and Imodium (loperamide hydrochloride). Common drug interactions include pain among males.

The phase IV clinical study analyzes what interactions people have when they take Trizivir and Imodium. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Trizivir?

Trizivir has active ingredients of abacavir sulfate; lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 2,813 Trizivir users. Check the latest studies of Trizivir.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 04, 2026

17 people who take Trizivir and Imodium together, and have interactions are studied.

Trizivir and Imodium drug interactions.

What are the common drug interactions of Trizivir and Imodium, by gender? *:

female:

n/a

male:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Asthenia (weakness)
  4. Chronic kidney disease
  5. Cough
  6. Decreased activity
  7. Drug ineffective
  8. Fatigue (feeling of tiredness)
  9. Gastric haemorrhage (bleeding stomach)
  10. Haemoglobin decreased

What are the common drug interactions of Trizivir and Imodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Asthenia (weakness)
  2. Fatigue (feeling of tiredness)
  3. Headache (pain in head)
  4. Nausea (feeling of having an urge to vomit)
  5. Rash

30-39:

  1. Abdominal pain
  2. Cough
  3. Gastric haemorrhage (bleeding stomach)
  4. Haemoglobin decreased
  5. Hypersensitivity
  6. Ileus (a painful obstruction of the ileum or other part of the intestine)
  7. Nausea (feeling of having an urge to vomit)
  8. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  9. Pyrexia (fever)
  10. Rhinorrhoea (watery mucus discharge from the nose)

40-49:

  1. Anaemia (lack of blood)
  2. Chest pain
  3. Dyspnoea exertional (breathlessness or shortness of breath)
  4. Fatigue (feeling of tiredness)
  5. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

50-59:

  1. Arthralgia (joint pain)
  2. Chronic kidney disease
  3. Decreased activity
  4. Drug ineffective
  5. Impaired work ability
  6. Myalgia (muscle pain)
  7. Pain in extremity
  8. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  9. Quality of life decreased
  10. Asthenia (weakness)

60+:

  1. Abdominal pain
  2. Asthma
  3. Bowen's disease (early stage of skin cancer)
  4. Hypersensitivity
  5. Productive cough
  6. Squamous cell carcinoma (a cancer of a kind of epithelial cell)

* Approximation only. Some reports may have incomplete information.

Do you take Trizivir and Imodium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Trizivir and Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trizivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trizivir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on abacavir sulfate; lamivudine; zidovudine and loperamide hydrochloride (the active ingredients of Trizivir and Imodium, respectively), and Trizivir and Imodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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