Trusopt and Aldactone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trusopt (dorzolamide hydrochloride) and Aldactone (spironolactone). Common drug interactions include abdominal pain among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Trusopt and Aldactone. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Trusopt?

Trusopt has active ingredients of dorzolamide hydrochloride. It is often used in glaucoma. eHealthMe is studying from 3,165 Trusopt users. Check the latest studies of Trusopt.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

On Aug, 08, 2026

48 people who take Trusopt and Aldactone together, and have interactions are studied.

Trusopt and Aldactone drug interactions.

What are the common drug interactions of Trusopt and Aldactone, by gender? *:

female:

Abdominal pain
Depression
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Vomiting
Anxiety
Aortic valve stenosis (narrowing of the aortic valve)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bladder mass
Blood cholesterol increased
Blood glucose increased

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Anaemia (lack of blood)
Arthropathy
Back pain
Blood immunoglobulin g increased
Bone disorder
Cardiac arrest
Cardiac asthma (wheezing, coughing or shortness of breath due to congestive heart failure)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)

What are the common drug interactions of Trusopt and Aldactone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Pain in jaw
Vomiting
Asthenia (weakness)
Cough
Dizziness
Headache (pain in head)
Nausea (feeling of having an urge to vomit)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Fall
Osteonecrosis of jaw (death of bone of jaw)
Diarrhoea
Hypokalaemia (low potassium)
Pain
Syncope (loss of consciousness with an inability to maintain postural tone)
Arthralgia (joint pain)
Tooth loss
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)

What are the existing conditions these people have? *

Depression: 20 people, 41.67%
Stable Angina (a constant chest pain): 13 people, 27.08%
Multiple Myeloma (cancer of the plasma cells): 11 people, 22.92%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 11 people, 22.92%
Arrhythmias (irregular heartbeat): 11 people, 22.92%
High Blood Pressure: 9 people, 18.75%
Cardiac Failure Congestive: 7 people, 14.58%
Breast Cancer Metastatic: 7 people, 14.58%
Breast Cancer: 7 people, 14.58%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 14.58%

* Approximation only. Some reports may have incomplete information.

Do you take Trusopt and Aldactone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously