Trusopt and Azopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trusopt (dorzolamide hydrochloride) and Azopt (brinzolamide). Common drug interactions include growth of eyelashes among females and eye irritation among males.

The phase IV clinical study analyzes what interactions people have when they take Trusopt and Azopt. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Trusopt?

Trusopt has active ingredients of dorzolamide hydrochloride. It is often used in glaucoma. eHealthMe is studying from 3,165 Trusopt users. Check the latest studies of Trusopt.

What is Azopt?

Azopt has active ingredients of brinzolamide. It is often used in glaucoma. eHealthMe is studying from 8,058 Azopt users. Check the latest studies of Azopt.

On Jul, 12, 2026

57 people who take Trusopt and Azopt together, and have interactions are studied.

What are the common drug interactions of Trusopt and Azopt, by gender? *:

female:

Growth of eyelashes
Headache (pain in head)
Therapeutic response decreased (less preventive response)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Choroidal detachment (separation of vascular layer of the eye)
Conjunctival hyperaemia (congestion of conjunctival vessels)
Depression
Dry mouth

male:

Eye irritation
Conjunctival hyperaemia (congestion of conjunctival vessels)
Diarrhoea
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Palpitations (feelings or sensations that your heart is pounding or racing)
Throat irritation
Angle closure glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity)
Anterior chamber flare (flare in the anterior chamber)
Blepharitis (chronic inflammation of the eyelid)

What are the common drug interactions of Trusopt and Azopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Nausea (feeling of having an urge to vomit)
Urticaria (rash of round, red welts on the skin that itch intensely)

30-39:

Optic nerve disorder (disease of optic nerve)
Optic nerve injury
Eye pain
Fatigue (feeling of tiredness)
Headache (pain in head)
Intraocular pressure increased
Visual field defect
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Impaired driving ability

40-49:

Dry eye (lack of adequate tears)
Dry mouth
Eye disorder

50-59:

Corneal disorder
Angle closure glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity)
Therapeutic response decreased (less preventive response)

60+:

Hypersensitivity
Drug ineffective
Conjunctival hyperaemia (congestion of conjunctival vessels)
Eyelid irritation
Alopecia (absence of hair from areas of the body)
Chest discomfort
Dizziness
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Eyelid disorder
Fear

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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