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Trusopt and Rescula drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trusopt (dorzolamide hydrochloride) and Rescula (unoprostone isopropyl). Common drug interactions include burning sensation among females and bradycardia among males.

The phase IV clinical study analyzes what interactions people have when they take Trusopt and Rescula. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Trusopt?

Trusopt has active ingredients of dorzolamide hydrochloride. It is often used in glaucoma. eHealthMe is studying from 3,165 Trusopt users. Check the latest studies of Trusopt.

What is Rescula?

Rescula has active ingredients of unoprostone isopropyl. eHealthMe is studying from 170 Rescula users. Check the latest studies of Rescula.

On Jul, 04, 2026

13 people who take Trusopt and Rescula together, and have interactions are studied.

Trusopt and Rescula drug interactions.

What are the common drug interactions of Trusopt and Rescula, by gender? *:

female:

  1. Burning sensation
  2. Corneal abrasion (loss of the surface of cornea)
  3. Corneal oedema (corneal swelling)
  4. Eye irritation
  5. Eye pain
  6. Headache (pain in head)
  7. Lacrimation increased
  8. Ocular pemphigoid (inflammatory autoimmune disorder characterized by blistering lesions that affect mucous membrane covering of eye)
  9. Smarting (stinging pain)
  10. Vision blurred

male:

  1. Bradycardia (abnormally slow heart action)
  2. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)

What are the common drug interactions of Trusopt and Rescula, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
  2. Conjunctival disorder (conjunctival disease)
  3. Corneal abrasion (loss of the surface of cornea)
  4. Corneal oedema (corneal swelling)
  5. Eye irritation
  6. Eye pain
  7. Headache (pain in head)
  8. Lacrimation increased
  9. Ocular pemphigoid (inflammatory autoimmune disorder characterized by blistering lesions that affect mucous membrane covering of eye)
  10. Smarting (stinging pain)

What are the existing conditions these people have? *

  1. Dry Eyes (lack of adequate tears): 1 person, 7.69%
  2. Diabetes: 1 person, 7.69%
  3. Dementia (madness): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Trusopt and Rescula?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Trusopt and Rescula:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trusopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rescula:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trusopt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rescula and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dorzolamide hydrochloride and unoprostone isopropyl (the active ingredients of Trusopt and Rescula, respectively), and Trusopt and Rescula (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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