Truvada and Clozaril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Truvada (emtricitabine; tenofovir disoproxil fumarate) and Clozaril (clozapine). Common drug interactions include asthenia among females and suicide attempt among males.

The phase IV clinical study analyzes what interactions people have when they take Truvada and Clozaril. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Truvada?

Truvada has active ingredients of emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 76,246 Truvada users. Check the latest studies of Truvada.

What is Clozaril?

Clozaril has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 65,127 Clozaril users. Check the latest studies of Clozaril.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

21 people who take Truvada and Clozaril together, and have interactions are studied.

What are the common drug interactions of Truvada and Clozaril, by gender? *:

female:

Asthenia (weakness)
Chest pain
Confusional state
Depressed level of consciousness
Feeling cold
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Influenza like illness
Myalgia (muscle pain)
Myocarditis (inflammation of heart muscle myocardium)
Pyrexia (fever)

male:

Suicide attempt
Anxiety
Blood urea increased
C-reactive protein increased
Confusional state
Delirium (wild excitement)
Drug level increased
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Hallucination, visual (seeing things that aren't there)
Hyperhidrosis (abnormally increased sweating)

What are the common drug interactions of Truvada and Clozaril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Multiple drug overdose intentional
Premature labour
Asthenia (weakness)
Chest pain
Circulatory collapse
Confusional state
Depressed level of consciousness
Dizziness

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Renal failure (kidney dysfunction)

50-59:

Feeling cold
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)

60+:

n/a

What are the existing conditions these people have? *

Personality Disorder: 8 people, 38.10%
Dissociative Identity Disorder: 8 people, 38.10%
Quit Smoking: 7 people, 33.33%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 14.29%
Chest Pain: 3 people, 14.29%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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