Turmeric and Silymarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Turmeric (turmeric) and Silymarin (milk thistle). Common drug interactions include fatigue among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Turmeric and Silymarin. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Turmeric?

Turmeric has active ingredients of turmeric. It is often used in inflammation. eHealthMe is studying from 16,563 Turmeric users. Check the latest studies of Turmeric.

What is Silymarin?

Silymarin has active ingredients of milk thistle. eHealthMe is studying from 793 Silymarin users. Check the latest studies of Silymarin.

On Jul, 15, 2026

24 people who take Turmeric and Silymarin together, and have interactions are studied.

Turmeric and Silymarin drug interactions.

What are the common drug interactions of Turmeric and Silymarin, by gender? *:

female:

Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Weight increased
Aphasia (damage to the parts of the brain that control language)
Asthma
Blood chloride increased
Blood cholesterol increased
Blood glucose increased
Blood potassium decreased

male:

Anaemia (lack of blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Pancreatic carcinoma (pancreatic cancer)
Ankylosing spondylitis (type of arthritis affecting the spine)
Blood pressure increased
Diarrhoea
Epistaxis (bleed from the nose)
Headache (pain in head)

What are the common drug interactions of Turmeric and Silymarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blood pressure increased
Diarrhoea
Epistaxis (bleed from the nose)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anaemia (lack of blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Pancreatic carcinoma (pancreatic cancer)
Aphasia (damage to the parts of the brain that control language)
Asthma
Blood chloride increased
Blood cholesterol increased
Blood glucose increased
Blood potassium decreased
Blood triglycerides increased

60+:

Gait disturbance
Abdominal discomfort
Dysuria (painful or difficult urination)
Epistaxis (bleed from the nose)
Fatigue (feeling of tiredness)
Headache (pain in head)
Insomnia (sleeplessness)
Myalgia (muscle pain)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 33.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 29.17%
Pituitary-Dependent Cushing's Syndrome (pituitary dependent hypercortisolism): 3 people, 12.50%
High Blood Pressure: 3 people, 12.50%
Pancreatic Insufficiency: 2 people, 8.33%
Pancreatic Carcinoma (pancreatic cancer): 2 people, 8.33%
Nausea (feeling of having an urge to vomit): 2 people, 8.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 8.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 8.33%
Hyperglycemia (high blood sugar): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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