Tygacil and Combivent drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tygacil (tigecycline) and Combivent (albuterol sulfate; ipratropium bromide). Common drug interactions include renal atrophy among females and pneumonia among males.
The phase IV clinical study analyzes what interactions people have when they take Tygacil and Combivent. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Tygacil?
Tygacil has active ingredients of tigecycline. eHealthMe is studying from 2,129 Tygacil users. Check the latest studies of Tygacil.
What is Combivent?
Combivent has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in asthma. eHealthMe is studying from 35,341 Combivent users. Check the latest studies of Combivent.
15 people who take Tygacil and Combivent together, and have interactions are studied.

What are the common drug interactions of Tygacil and Combivent, by gender? *:
female:
- Renal atrophy (wasting of kidney)
- Renal tubular necrosis (death of kidney tubules)
- Scab (a hard coating on the skin formed during the wound healing)
- Scratch
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Sinusitis (inflammation of sinus)
- Somatoform disorder (a mental disorder characterized by symptoms that suggest physical illness or injury)
- Somnambulism (sleep walking)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Spinal column stenosis (narrowing of spinal column)
male:
- Pneumonia
- Neutropenia (an abnormally low number of neutrophils)
- Arrhythmia (irregular heartbeat)
- Ventricular extrasystoles (premature cardiac contraction)
- Drug hypersensitivity
- Hepatosplenomegaly (enlargement of both the liver and the spleen)
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
- Infection
- Lymphadenitis (inflammation or enlargement of a lymph node)
- Oedema (fluid collection in tissue)
What are the common drug interactions of Tygacil and Combivent, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Drug hypersensitivity
- Hepatosplenomegaly (enlargement of both the liver and the spleen)
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
- Infection
- Lymphadenitis (inflammation or enlargement of a lymph node)
- Oedema (fluid collection in tissue)
- Oropharyngeal pain
40-49:
- Cystic fibrosis (disease of the secretary glands)
- Heart rate increased
- Lung infection
- Oxygen saturation decreased
- Pneumonia
- Secretion discharge
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Superinfection
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Pancreatitis (inflammation of pancreas)
50-59:
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Anxiety
- Depression
- Injury
- Renal tubular necrosis (death of kidney tubules)
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
60+:
- Pneumonia
- Neutropenia (an abnormally low number of neutrophils)
- Arrhythmia (irregular heartbeat)
- Ventricular extrasystoles (premature cardiac contraction)
- Blood creatinine increased
- Blood urea increased
- Death
What are the existing conditions these people have? *
- Stress And Anxiety: 3 people, 20.00%
- High Blood Cholesterol: 3 people, 20.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 20.00%
- Gastric Ph Decreased: 3 people, 20.00%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 20.00%
- Fever: 2 people, 13.33%
- Diabetes Mellitus Inadequate Control: 2 people, 13.33%
- Bronchopulmonary Aspergillosis Allergic (allergic lung disorder caused by aspergillus fungi): 2 people, 13.33%
- Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 6.67%
- Pneumonia: 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Tygacil and Combivent?
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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tygacil and Combivent:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tygacil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Combivent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tygacil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Combivent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on tigecycline and albuterol sulfate; ipratropium bromide (the active ingredients of Tygacil and Combivent, respectively), and Tygacil and Combivent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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