Tygacil and Fentanyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tygacil (tigecycline) and Fentanyl (fentanyl citrate). Common drug interactions include pancreatitis acute among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Tygacil and Fentanyl. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Tygacil?

Tygacil has active ingredients of tigecycline. eHealthMe is studying from 2,129 Tygacil users. Check the latest studies of Tygacil.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

On Jul, 11, 2026

26 people who take Tygacil and Fentanyl together, and have interactions are studied.

What are the common drug interactions of Tygacil and Fentanyl, by gender? *:

female:

Pancreatitis acute (sudden inflammation of pancreas)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Pyrexia (fever)
Blood potassium decreased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic coma
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal stoma complication (complication of an opening surgically made in digestive tract)
Hypotension (abnormally low blood pressure)

male:

Thrombocytopenia (decrease of platelets in blood)
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Loss of consciousness
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Nausea (feeling of having an urge to vomit)
Pneumonia
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the common drug interactions of Tygacil and Fentanyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal distension
Abdominal pain
Abdominal pain lower
Constipation
Faeces hard
Haematochezia (passage of stools containing blood)
Rectal haemorrhage (bleeding from anus)

40-49:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Gastrointestinal stoma complication (complication of an opening surgically made in digestive tract)
Hypotension (abnormally low blood pressure)
Multi-organ failure (multisystem organ failure)
Peritoneal disorder
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pyrexia (fever)
Renal tubular necrosis (death of kidney tubules)
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Activated partial thromboplastin time prolonged
Hypocoagulable state (abnormality of blood coagulation that increases the risk of thrombosis)
Pancreatitis acute (sudden inflammation of pancreas)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic coma
Hypofibrinogenaemia (a decrease in plasma fibrogen level)

60+:

Thrombocytopenia (decrease of platelets in blood)
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Loss of consciousness
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Nausea (feeling of having an urge to vomit)
Pneumonia
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the existing conditions these people have? *

Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 26.92%
Nausea (feeling of having an urge to vomit): 4 people, 15.38%
Constipation: 4 people, 15.38%
Hyperglycemia (high blood sugar): 4 people, 15.38%
Diabetes: 3 people, 11.54%
Staphylococcal Infection (an infection with staphylococcus bacteria): 2 people, 7.69%
Gastric Ulcer (stomach ulcer): 2 people, 7.69%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 7.69%
Anaemia (lack of blood): 2 people, 7.69%
C-Reactive Protein Increased: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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