Tylenol w/ codeine no. 2 and Tylenol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine no. 2 (acetaminophen; codeine phosphate) and Tylenol (acetaminophen). Common drug interactions include renal impairment among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine no. 2 and Tylenol. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine no. 2?

Tylenol w/ codeine no. 2 has active ingredients of acetaminophen; codeine phosphate. It is often used in back pain. eHealthMe is studying from 151 Tylenol w/ codeine no. 2 users. Check the latest studies of Tylenol w/ codeine no. 2.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,309 Tylenol users. Check the latest studies of Tylenol.

On Jul, 26, 2026

17 people who take Tylenol w/ codeine no. 2 and Tylenol together, and have interactions are studied.

Tylenol w/ codeine no. 2 and Tylenol drug interactions.

What are the common drug interactions of Tylenol W/ Codeine No. 2 and Tylenol, by gender? *:

female:

Renal impairment (severely reduced kidney function)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Septic shock (shock due to blood infection)
Tendon disorder (disease of tendon)
Abdominal pain upper
Blood creatinine increased
Colitis (inflammation of colon)
Confusional state
Diarrhoea
Dizziness

male:

Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Cough
Death
Decreased interest
Diplegia (paralysis of corresponding parts on both sides of the body)
Dyspepsia (indigestion)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Ejection fraction decreased (systolic heart failure)

What are the common drug interactions of Tylenol W/ Codeine No. 2 and Tylenol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pain in jaw
Toothache (tooth pain)
Urinary retention (the inability to completely or partially empty the bladder)
Viral infection
Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)

50-59:

Arthralgia (joint pain)
Exostosis (formation of new bone on the surface of a bone)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain in extremity
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Tendon disorder (disease of tendon)
Epistaxis (bleed from the nose)
Haemoglobin decreased
Heart rate increased

60+:

Abdominal pain upper
Arthralgia (joint pain)
Personality disorder
Blood creatinine increased
Colitis (inflammation of colon)
Confusional state
Death
Diarrhoea
Dizziness
Haemoglobin decreased

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 3 people, 17.65%
Metastases To Bone (cancer spreads to bone): 3 people, 17.65%
High Blood Pressure: 3 people, 17.65%
Hepatitis C: 3 people, 17.65%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 17.65%
Sleep Disorder: 2 people, 11.76%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 11.76%
Osteoporosis (bones weak and more likely to break): 2 people, 11.76%
Gastric Disorder (disease of stomach): 2 people, 11.76%
Cardiac Failure Congestive: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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