Tylenol w/ codeine no. 3 and Asacol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate) and Asacol (mesalamine). Common drug interactions include diarrhoea among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine no. 3 and Asacol. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine no. 3?

Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.

What is Asacol?

Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.

On Jul, 13, 2026

29 people who take Tylenol w/ codeine no. 3 and Asacol together, and have interactions are studied.

Tylenol w/ codeine no. 3 and Asacol drug interactions.

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Asacol, by gender? *:

female:

Diarrhoea
Drug ineffective
Nausea (feeling of having an urge to vomit)
Abdominal pain
Adrenal mass
Anaemia (lack of blood)
Decreased appetite
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Fatigue (feeling of tiredness)
Feeling hot

male:

Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Meralgia paraesthetica (a neurological (nerve) condition that causes pain in the outer thigh)
Pain in extremity
Therapeutic response decreased (less preventive response)
Weight increased
Diarrhoea haemorrhagic (bloody diarrhoea)
Haematochezia (passage of stools containing blood)
Inflammatory bowel disease
Abdominal distension

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Asacol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Diarrhoea haemorrhagic (bloody diarrhoea)
Haematochezia (passage of stools containing blood)
Inflammatory bowel disease

20-29:

Epistaxis (bleed from the nose)
Pulmonary haemorrhage (acute bleeding from the lung)
Sinusitis (inflammation of sinus)

30-39:

n/a

40-49:

Fatigue (feeling of tiredness)
Anxiety
Attention deficit/hyperactivity disorder
Drug ineffective
Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Heart rate increased
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)

50-59:

Diarrhoea
Food poisoning (poison in food)
Haematemesis (vomiting of blood)
Heart rate increased
Hypertension (high blood pressure)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Road traffic accident
Vomiting

60+:

Diarrhoea
Abdominal pain
Splenic artery aneurysm (enlargement of splenic artery)
Weight decreased
Bone pain
Dehydration (dryness resulting from the removal of water)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Asthenia (weakness)
Bradycardia (abnormally slow heart action)
Cardioactive drug level increased

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 10 people, 34.48%
Osteoporosis (bones weak and more likely to break): 6 people, 20.69%
Abdominal Pain: 4 people, 13.79%
Nervousness: 2 people, 6.90%
Muscle Spasms (muscle contraction): 2 people, 6.90%
Inflammation: 2 people, 6.90%
High Blood Pressure: 2 people, 6.90%
Diarrhea: 2 people, 6.90%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 6.90%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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