Tylenol w/ codeine no. 3 and Nitrostat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate) and Nitrostat (nitroglycerin). Common drug interactions include chronic obstructive pulmonary disease among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine no. 3 and Nitrostat. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine no. 3?

Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

37 people who take Tylenol w/ codeine no. 3 and Nitrostat together, and have interactions are studied.

Tylenol w/ codeine no. 3 and Nitrostat drug interactions.

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Nitrostat, by gender? *:

female:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Bedridden
Abdominal pain upper
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blindness unilateral
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Depression
Diabetic retinopathy (damage to the retina caused by complications of diabetes)

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Blindness unilateral
Respiratory failure (inadequate gas exchange by the respiratory system)
Acute myocardial infarction (acute heart attack)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Blood cholesterol increased
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac failure congestive
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Death

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Nitrostat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Bedridden
Blood cholesterol increased
Muscle spasms (muscle contraction)

50-59:

Blindness unilateral
Eye haemorrhage (bleeding in the eye)
Malignant melanoma (skin cancer rises from melancytes)
Acute myocardial infarction (acute heart attack)
Blood cholesterol increased
Drug effect decreased
Eye disorder
Eye pain
Headache (pain in head)
Heart rate decreased

60+:

Abdominal pain upper
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Osteoporosis (bones weak and more likely to break)
Ovarian cyst (fluid filled sac of the ovary)
Retinal tear
Retinal vein occlusion (a blockage of the small veins that carry blood away from the retina)
Spinal osteoarthritis (joint cartilage loss in spine)
Vitreous haemorrhage (intraocular (inside the eye) bleeding)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depressed level of consciousness

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 14 people, 37.84%
High Blood Cholesterol: 13 people, 35.14%
Cardiac Disorder: 13 people, 35.14%
Migraine (headache): 13 people, 35.14%
Insomnia (sleeplessness): 13 people, 35.14%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 13 people, 35.14%
Diabetes: 13 people, 35.14%
Muscle Spasms (muscle contraction): 12 people, 32.43%
Lung Disorder (lung disease): 12 people, 32.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 32.43%

* Approximation only. Some reports may have incomplete information.

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